| Gene Symbol |
PIK3C2G
|
| Entrez Gene |
5288
|
| Alt Symbol |
PI3K-C2-gamma, PI3K-C2GAMMA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
|
| Other Description |
PTDINS-3-kinase C2 gamma|phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma|phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide|phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma|phosphoinositide-3-kinase, class 2, gamma polypeptide|ptdIns-3-kinase C2 subunit gamma
|
| Swissprots |
A1L3U0 O75747
|
| Accessions |
EAW96387 O75747 AI478164 AJ000008 CAA03853 BC130277 AAI30278 BC144133 BC144134 AAI44135 BX092808 XM_006719088 XP_006719151 XM_011520693 XP_011518995 XM_011520694 XP_011518996 XM_011520695 XP_011518997 XM_011520696 XP_011518998 XM_011520697 XP_011518999 XM_011520698 XP_011519000 XM_011520699 XP_011519001 XM_011520700 XP_011519002 XM_011520701 XP_011519003 XM_011520702 XP_011519004 XR_931307 NM_001288772 NP_001275701 NM_001288774 NP_001275703 NM_004570 NP_004561
|
| Function |
Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. May play a role in SDF1A-stimulated chemotaxis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in liver, prostate and testis. Lower levels in small intestine, kidney and pancreas. {ECO:0000269|PubMed:9878262}.
|
| Top Pathways |
Inositol phosphate metabolism, Phosphatidylinositol signaling system
|