APOA1

Gene Symbol	APOA1
Entrez Gene	335
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	apolipoprotein A-I
Other Description	apo-AI
Swissprots	Q9UCT8 A8K866 P02647 Q9UCS8 Q6Q785 Q6LDN9
Accessions	AAA51746 AAB59514 AAD34604 AAL92035 AAQ91811 AAS68227 ACA05932 ACA05933 ACA05934 ACA05935 ACA05936 AFU51373 CAA25519 CAA30377 EAW67274 EAW67275 EAW67276 EAW67277 P02647 A14829 CAA01198 A15879 CAA01253 AK292231 BAF84920 BC005380 AAH05380 BC110286 AAI10287 DQ893073 ABM83999 DQ896330 ABM87329 M11791 AAA35545 M27875 AAA62829 M29068 AAA51747 X00566 CAA25232 X02162 CAA26097 XM_005271539 XP_005271596 XM_005271540 XP_005271597 NM_000039 NP_000030
Function	Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. {ECO:0000269|PubMed:1909888}.
Subcellular Location	Secreted.
Tissue Specificity	Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease. {ECO:0000269|PubMed:12576517}.
Top Pathways	PPAR signaling pathway, African trypanosomiasis, Fat digestion and absorption, Vitamin digestion and absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Apolipoprotein A I full length protein - ab155731 from Abcam Category Protein Prices $410.00 Sizes 50 µg Source HEK 293 cells Species Human

Human Apolipoprotein A I full length protein - ab168890 from Abcam Category Protein Prices $345.00 Sizes 500 µg Source Mammalian Species Human

Human Apolipoprotein A I full length protein - ab90760 from Abcam Category Protein Prices $356.00 Sizes 500 µg Source Native Species Human

Human Apolipoprotein A I full length protein - ab151681 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human Apolipoprotein A I full length protein - ab50239 from Abcam Category Protein Prices $110.00, $235.00 Sizes 20 µg, 100 µg Source E. coli Species Human

Human Apolipoprotein A I peptide - ab66674 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human HDL full length protein - ab167790 from Abcam Category Protein Source Native Species Human

Mouse Apolipoprotein A I full length protein - ab202174 from Abcam Category Protein Source E. coli Species Mouse

APOA1 / Apolipoprotein A 1 Antibody Blocking Peptide - LS-E19525 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOA1 / Apolipoprotein A 1 Antibody Blocking Peptide - LS-E8933 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOA1 / Apolipoprotein A 1 Antibody Blocking Peptide - LS-E28049 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOA1 / Apolipoprotein A 1 Antibody Blocking Peptide - LS-E30670 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

APOA1 / Apolipoprotein A 1 Antibody Blocking Peptide - LS-E31106 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Human Apolipoprotein A-I/ApoA1 Protein - NBP2-34869 from Novus Biologicals Category Protein Prices $75.00 Sizes 20 µg Species Human

Recombinant Human Apolipoprotein A-I/ApoA1 Protein - H00000335-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Source Wheat Germ Species Human

Recombinant Human Apolipoprotein A-I/ApoA1 Protein - NBP1-30197 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

Apolipoprotein A-I/ApoA1 Blocking Peptide - NBP1-77008PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Apolipoprotein A-I/ApoA1 Peptide - NBP1-76563PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

Apolipoprotein A-I/ApoA1 Protein - NBP1-99229 from Novus Biologicals Category Protein Species Human

Recombinant Human Apolipoprotein A-I/ApoA1 Protein - NBP1-99129 from Novus Biologicals Category Protein Prices $80.00 Sizes 20 µg Source E. coli Species Human

APOA1-Antibody-C-term-Blocking-peptide - BP12631b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

APOA1-Antibody-N-term-Blocking-Peptide - BP7414a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Apolipoprotein A1 recombinant protein - GTX65006 from GeneTex Category Protein Prices $199.00 Sizes 20 μg Source E. coli Species Human

Apolipoprotein A1 Peptide - GTX85115-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Apo AI Protein (OPMA04161) - OPMA04161 from Aviva Systems Biology Category Protein Prices $995.00 Sizes 50 µg Source Mouse Plasma

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