Polr2c

Gene Symbol Polr2c
Entrez Gene 20021
Alt Symbol 33kDa, RPB3, Rpo2-3, mRBP31
Species Mouse
Gene Type protein-coding
Description polymerase (RNA) II (DNA directed) polypeptide C
Other Description DNA-directed RNA polymerase II 33 kDa polypeptide|DNA-directed RNA polymerase II subunit C|DNA-directed RNA polymerase II subunit RPB3|RNA polymerase II 3|RNA polymerase II subunit 3|RNA polymerase II subunit B3|RPB31|RPB33
Swissprots P97760
Accessions P97760 AK137796 BAE23500 AK146763 BAE27415 AK151270 BAE30257 AK160053 BAE35592 AK192118 BC002023 AAH02023 BC099548 AAH99548 D83999 BAA12205 NM_009090 NP_033116
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}.
Top Pathways Huntington's disease, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism