| Gene Symbol |
Coq7
|
| Entrez Gene |
12850
|
| Alt Symbol |
clk-1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
demethyl-Q 7
|
| Other Description |
coenzyme Q biosynthesis protein 7 homolog|timing protein clk-1 homolog|ubiquinone biosynthesis protein COQ7 homolog
|
| Swissprots |
Q9R0D7 P97478
|
| Accessions |
EDL17129 EDL17130 P97478 AF053770 AAC69179 AF080580 AAC31572 AF098949 AAD43649 AK137841 AK158380 BAE34481 BC028276 AAH28276 BC038681 AAH38681 BY284216 U81277 AAC53055 XM_006507296 XP_006507359 NM_001304758 NP_001291687 NM_009940 NP_034070
|
| Function |
Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator. {ECO:0000269|PubMed:19478076}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:11387338}; Peripheral membrane protein {ECO:0000269|PubMed:11387338}; Matrix side {ECO:0000269|PubMed:11387338}. Note=Synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane.
|
| Tissue Specificity |
Highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney. {ECO:0000269|PubMed:11511092}.
|
| Top Pathways |
Ubiquinone and other terpenoid-quinone biosynthesis
|
