| Gene Symbol | SRP68 |
|---|---|
| Entrez Gene | 855833 |
| Alt Symbol | - |
| Species | Yeast |
| Gene Type | protein-coding |
| Description | Srp68p |
| Other Description | - |
| Swissprots | P38687 D6W3C8 |
| Accessions | DAA11194 P38687 NM_001184057 NP_015081 |
| Function | Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:11352936}. |
| Top Pathways | Protein export |
Recombinant Saccharomyces cerevisiae Signal recognition particle subunit SRP68(SRP68) ,partial - CSB-YP336478SVG CSB-EP336478SVG CSB-BP336478SVG CSB-MP336478SVG from Cusabio
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Signal recognition particle subunit SRP68 (SRP68), partial, Recombinant Protein - MBS1034022 from MyBioSource
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