ACMSD

Gene Symbol ACMSD
Entrez Gene 130013
Alt Symbol -
Species Human
Gene Type protein-coding
Description aminocarboxymuconate semialdehyde decarboxylase
Other Description 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase|picolinate carboxylase
Swissprots Q8TDX5 Q96KY2 Q3B7X3 Q53SR5
Accessions AAY14997 EAX11649 EAX11650 EAX11651 EAX11652 Q8TDX5 AB071418 BAB86938 AK125008 BAC86023 BC016018 AAH16018 BC107420 AAI07421 BG428338 XM_005263586 XP_005263643 XM_005263587 XP_005263644 XM_005263588 XP_005263645 XM_005263589 XP_005263646 XM_005263590 XP_005263647 XM_011510592 XP_011508894 NM_001307983 NP_001294912 NM_138326 NP_612199
Function Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway. {ECO:0000269|PubMed:19843166}.
Top Pathways Tryptophan metabolism

ACMSD CRISPR/Cas9 KO Plasmid (h) - sc-410293 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACMSD HDR Plasmid (h) - sc-410293-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACMSD Double Nickase Plasmid (h) - sc-410293-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACMSD Double Nickase Plasmid (h2) - sc-410293-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACMSD CRISPR Activation Plasmid (h) - sc-410293-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACMSD CRISPR Activation Plasmid (h2) - sc-410293-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACMSD Lentiviral Activation Particles (h) - sc-410293-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACMSD Lentiviral Activation Particles (h2) - sc-410293-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACMSD siRNA (h) - sc-94727 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACMSD shRNA Plasmid (h) - sc-94727-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACMSD shRNA (h) Lentiviral Particles - sc-94727-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACMSD RNAi - H00130013-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU083221 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2720 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2720 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00412 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00412

ACMSD siRNA (Human) - CRJ5017 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACMSD - MBS8238534 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ACMSD (NM_138326.2) - SHH230302 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ACMSD(NM_138326.2) - SHG029629 from Creative biogene

Category siRNA
Species Reactivities Human

Human ACMSD siRNA - orb275518 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACMSD shRNA Plasmid (Human) - CHJ5017 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ACMSD miRNA 3'UTR clone - MiUTR1H-00104 from Creative biogene

Species Reactivities Human
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