| Gene Symbol |
FCER1G
|
| Entrez Gene |
2207
|
| Alt Symbol |
FCRG
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
|
| Other Description |
Fc receptor gamma-chain|fc-epsilon RI-gamma|fcRgamma|fceRI gamma|high affinity immunoglobulin epsilon receptor subunit gamma|immunoglobulin E receptor, high affinity, gamma chain
|
| Swissprots |
P30273 Q5VTW4
|
| Accessions |
CBK51078 CCF76977 EAW52623 EAW52624 P30273 AK307102 BC033872 AAH33872 DQ890782 ABM81708 EU176502 ABW03303 M33195 AAA35828 NM_004106 NP_004097
|
| Function |
Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin. {ECO:0000269|PubMed:8611682}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:8611682}; Single-pass type I membrane protein {ECO:0000269|PubMed:8611682}.
|
| Top Pathways |
Natural killer cell mediated cytotoxicity, Fc epsilon RI signaling pathway, Asthma, Tuberculosis, Sphingolipid signaling pathway
|
