IRAK2

Gene Symbol	IRAK2
Entrez Gene	3656
Alt Symbol	IRAK-2
Species	Human
Gene Type	protein-coding
Description	interleukin-1 receptor-associated kinase 2
Other Description	interleukin-1 receptor associated kinase-2|interleukin-1 receptor-associated kinase-like 2
Swissprots	Q08AG6 Q5K546 O43187 B4DQZ6
Accessions	EAW64069 O43187 AF026273 AAB87669 AJ496794 CAD43180 AK299033 BAG61108 AK312841 BAG35695 AL538890 AL556221 BC125184 AAI25185 BG682610 XM_011533680 XP_011531982 XR_245126 NM_001570 NP_001561
Function	Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. {ECO:0000269|PubMed:10383454, ECO:0000269|PubMed:9374458}.
Tissue Specificity	Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes. {ECO:0000269|PubMed:9374458}.
Top Pathways	Apoptosis, Neurotrophin signaling pathway, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IRAK-2 CRISPR/Cas9 KO Plasmid (h) - sc-404304 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-2 HDR Plasmid (h) - sc-404304-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-2 Double Nickase Plasmid (h) - sc-404304-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-2 Double Nickase Plasmid (h2) - sc-404304-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-2 CRISPR Activation Plasmid (h) - sc-404304-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-2 CRISPR Activation Plasmid (h2) - sc-404304-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-2 Lentiviral Activation Particles (h) - sc-404304-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-2 Lentiviral Activation Particles (h2) - sc-404304-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRAK-2 siRNA (h) - sc-106916 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IRAK-2 shRNA Plasmid (h) - sc-106916-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IRAK-2 shRNA (h) Lentiviral Particles - sc-106916-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU053661 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0976 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0977 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0978 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2002 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2002 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09678 from Sigma-Aldrich Category miRNA

IRAK2 siRNA (Human) - CRH2450 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

IRAK2 RNAi - H00003656-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

IRAK2 - MBS8238971 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human IRAK2 (NM_001570.3) - SHH320509 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human IRAK2(NM_001570.3) - SHL173352 from Creative biogene Category siRNA Species Reactivities Human

IRAK2 shRNA Plasmid (Human) - CHH2450 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

IRAK2 miRNA 3'UTR clone - MiUTR1H-04987 from Creative biogene Species Reactivities Human

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