H2AFX

Gene Symbol	H2AFX
Entrez Gene	3014
Alt Symbol	H2A.X, H2A/X, H2AX
Species	Human
Gene Type	protein-coding
Description	H2A histone family, member X
Other Description	H2AX histone|histone H2A.x|histone H2AX
Swissprots	Q6IAS5 P16104 Q4ZGJ7
Accessions	AAY22178 EAW67451 P16104 BC004915 AAH04915 BC011694 AAH11694 BC013416 AAH13416 CR457079 CAG33360 X14850 CAA32968 NM_002105 NP_002096
Function	Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation. {ECO:0000269|PubMed:10959836, ECO:0000269|PubMed:12419185, ECO:0000269|PubMed:12607005, ECO:0000269|PubMed:15201865}.
Subcellular Location	Nucleus. Chromosome.
Top Pathways	Systemic lupus erythematosus, Alcoholism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

H2AFX - MBS1269757 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC004915

Human H2AFX ORF clone(NM_002105.2) - CDCL184491 from Creative Biomart Species Human Accession NM_002105.2

Human H2AFX ORF Clone(NM_002105.2) - CDCL165677 from Creative Biomart Species Human Accession NM_002105.2

Human Histone H2AX / H2AFX Gene cDNA Clone (full-length ORF Clone) - HG10023-M from Sino Biological Species Human Accession NM_002105.2

Human H2AFX Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10023-ACG from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10023-NF from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10023-CF from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10023-NM from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10023-CM from Sino Biological Species Human

Human Histone H2AX / H2AFX Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG10023-M-F from Sino Biological Species Human Accession NM_002105.2

Human H2AFX Gene ORF cDNA clone expression plasmid, N-His tag - HG10023-NH from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10023-ACR from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10023-ANR from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10023-ANG from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, C-HA tag - HG10023-CY from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, C-His tag - HG10023-CH from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid - HG10023-UT from Sino Biological Species Human

Human H2AFX Gene ORF cDNA clone expression plasmid, N-HA tag - HG10023-NY from Sino Biological Species Human

Human H2AFX ORF clone(NM_002105.2) - CDCL184491 from Creative biogene Species Human

Human H2AFX ORF Clone (BC004915) - CDCS410616 from Creative biogene Species Human Accession P16104

Human Histone H2AX gene - orb90645 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Search more