| Gene Symbol | PCK2 |
|---|---|
| Entrez Gene | 5106 |
| Alt Symbol | PEPCK, PEPCK-M, PEPCK2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| Other Description | PEP carboxykinase|phosphoenolpyruvate carboxykinase [GTP], mitochondrial|phosphopyruvate carboxylase |
| Swissprots | O43253 Q16822 Q9BV62 Q86U01 |
| Accessions | BAD36844 CAA12234 CAA72272 EAW66115 Q16822 AK129934 AK301400 BAG62935 AK307913 AK311710 AK316206 BAH14577 BC001454 AAH01454 BQ957219 BU153045 BU623248 BX248272 CAD62600 CA444720 CN359636 CR456913 CAG33194 DA645036 DB028389 HY022221 X92720 CAA63380 XM_006720158 XP_006720221 XM_011536813 XP_011535115 NM_001018073 NP_001018083 NM_001291556 NP_001278485 NM_001308054 NP_001294983 NM_004563 NP_004554 |
| Function | Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. {ECO:0000250}. |
| Subcellular Location | Mitochondrion. |
| Top Pathways | Glucagon signaling pathway, Glycolysis / Gluconeogenesis, AMPK signaling pathway, PI3K-Akt signaling pathway, Proximal tubule bicarbonate reclamation |