| Gene Symbol |
PCK2
|
| Entrez Gene |
5106
|
| Alt Symbol |
PEPCK, PEPCK-M, PEPCK2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
| Other Description |
PEP carboxykinase|phosphoenolpyruvate carboxykinase [GTP], mitochondrial|phosphopyruvate carboxylase
|
| Swissprots |
O43253 Q16822 Q9BV62 Q86U01
|
| Accessions |
BAD36844 CAA12234 CAA72272 EAW66115 Q16822 AK129934 AK301400 BAG62935 AK307913 AK311710 AK316206 BAH14577 BC001454 AAH01454 BQ957219 BU153045 BU623248 BX248272 CAD62600 CA444720 CN359636 CR456913 CAG33194 DA645036 DB028389 HY022221 X92720 CAA63380 XM_006720158 XP_006720221 XM_011536813 XP_011535115 NM_001018073 NP_001018083 NM_001291556 NP_001278485 NM_001308054 NP_001294983 NM_004563 NP_004554
|
| Function |
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion.
|
| Top Pathways |
Glucagon signaling pathway, Glycolysis / Gluconeogenesis, AMPK signaling pathway, PI3K-Akt signaling pathway, Proximal tubule bicarbonate reclamation
|
![Western Blot: PCK2 Overexpression Lysate (Adult Normal) [NBL1-14180] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PCK2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6960_PCK2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14180-img0002.jpg)