C2

Gene Symbol	C2
Entrez Gene	717
Alt Symbol	ARMD14, CO2
Species	Human
Gene Type	protein-coding
Description	complement component 2
Other Description	C3/C5 convertase|complement C2|complement component C2
Swissprots	Q13904 B4DPF3 P06681 E9PFN7 B4DV20 O19694
Accessions	AAA51854 AAA59624 AAA59649 AAB67975 AAB97607 AAQ15273 BAB63292 CAA54545 EAX03548 EAX03549 P06681 AA740316 AK096258 BAG53241 AK222537 BAD96257 AK222783 BAD96503 AK298311 BAG60565 AK298808 BAG60943 AK300892 BAG62532 AK300930 BAG62560 AK307930 AK312581 BAG35475 AW515583 BC029781 AAH29781 BC043484 AAH43484 BX537504 CAD97767 DC349268 DC358441 DC362624 N63977 X04481 CAA28169 NM_000063 NP_000054 NM_001145903 NP_001139375 NM_001178063 NP_001171534 NM_001282457 NP_001269386 NM_001282458 NP_001269387 NM_001282459 NP_001269388
Function	Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Systemic lupus erythematosus, Staphylococcus aureus infection, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human C2 peptide - ab94384 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human C2 protein fragment - ab112728 from Abcam Category Protein Prices $297.00 Sizes 200 µg Source E. coli Species Human

Complement C2 Antibody Blocking Peptide - LS-E385 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

C2-Antibody-N-term-Blocking-peptide - BP10662a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Complement Component C2, CF - 1936-SE-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala21-Leu752, with a C-terminal 6-His tag

C2 Protein Lysate (APL10421) - APL10421 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

C2 Protein Lysate (APL10656) - APL10656 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

C2 Protein Lysate (APL10752) - APL10752 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

C2 Protein Lysate (APL10753) - APL10753 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

Complement C2 Blocking Peptide - 33R-2634 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Complement C2 Blocking Peptide - 33R-4079 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Complement Component 2 Protein - abx066050 from Abbexa Category Protein Source E.coli Species Human

Complement C2 - H00000717-P02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Complement C2 - H00000717-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Complement C2 - P5886 from Acris Antibodies Category Protein Prices $790.00 Sizes 200 µg Species Human

C2 fusion protein - ag13610 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human C2 - C2-26739TH from Creative Biomart Category Protein Source E. coli

Recombinant Human C2, His tagged - C2-6878H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human C2, Fc tagged - C2-7265H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human Complement Component 2, His-tagged - C2-598H from Creative Biomart Category Protein Source Human Cells (HEK293) .

Recombinant Human Complement Component 2, Fc Chimera - C2-599H from Creative Biomart Category Protein Source Human Cells (HEK293) .

Native Human C2 Protein - C2-98H from Creative Biomart Category Protein Source Normal human serum (shown by certified tests to be negative for HBsAg and for antibodies to HCV, HIV-1 and HIV-II). Species Human

Recombinant Complement Component 2 (C2) - RPA862Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Complement Component 2 (C2) - RPA862Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Complement Component 2 (C2) - RPA862Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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