ANK1

Gene Symbol ANK1
Entrez Gene 286
Alt Symbol ANK, SPH1, SPH2
Species Human
Gene Type protein-coding
Description ankyrin 1, erythrocytic
Other Description ANK-1|ankyrin-1|ankyrin-R|erythrocyte ankyrin
Swissprots E5RFL7 Q8N604 O43400 P16157 Q13768 Q59FP2 Q53ER1 A0PJN8 A6NJ23 Q99407
Accessions AAB46776 AAB47804 AAB47805 EAW63241 EAW63242 EAW63243 EAW63244 EAW63245 EAW63246 EAW63247 EAW63248 EAW63249 EAW63250 P16157 AA404587 AB209418 BAD92655 AI167814 AI684839 AK126647 BAG54351 AK129864 AK223578 BAD97298 BC007930 AAH07930 BC014467 BC030957 AAH30957 BC117121 AAI17122 BC156401 AAI56402 BX647936 F28948 HQ447752 ADQ32237 M28880 AAA51732 N63745 X16609 CAA34610 XM_005273476 XP_005273533 XM_011544490 XP_011542792 XM_011544491 XP_011542793 XM_011544492 XP_011542794 XM_011544493 XP_011542795 XM_011544494 XP_011542796 XM_011544495 XP_011542797 XM_011544496 XP_011542798 XM_011544497 XP_011542799 XM_011544498 XP_011542800 XM_011544499 XP_011542801 XM_011544500 XP_011542802 XM_011544501 XP_011542803 XM_011544502 XP_011542804 XM_011544503 XP_011542805 XM_011544504 XP_011542806 XM_011544505 XP_011542807 XM_011544506 XP_011542808 XR_949389 NM_000037 NP_000028 NM_001142445 NP_001135917 NM_001142446 NP_001135918 NM_020475 NP_065208 NM_020476 NP_065209 NM_020477 NP_065210 NM_020478 NP_065211 NM_020480 NP_065213 NM_020479 NM_020481
Function Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions. {ECO:0000269|PubMed:12456646}.
Subcellular Location Isoform Mu20: Sarcoplasmic reticulum {ECO:0000305}.
Tissue Specificity Isoform Mu17, isoform Mu18, isoform Mu19 and isoform Mu20 are expressed in skeletal muscle. Isoform Br21 is expressed in brain. {ECO:0000269|PubMed:9430667}.
Top Pathways Proteoglycans in cancer

ANK-1 (8G6) - sc-81550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
ANK-1 (8G6): sc-81550. Western blot analysis of ANK-1 expression in mouse brain tissue extract.

Ankyrin-1 (D-3) - sc-374105 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ankyrin-1 (D-3): sc-374105. Western blot analysis of Ankyrin-1 expression in HEL 92.1.7 whole cell lysate.

Ankyrin-1 (H-125) - sc-135329 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ankyrin-1 (H-125): sc-135329. Western blot analysis of Ankyrin-1 expression in non-transfected: sc-117752 (A) and human Ankyrin-1 transfected: sc-371924 (B) 293T whole cell lysates.

Ankyrin-1 (H-4) - sc-374240 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ankyrin-1 (H-4): sc-374240. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Ankyrin-1 (8C3) - sc-12733 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ankyrin-1 (8C3): sc-12733. Western blot analysis of Ankyrin-1 expression in HEL 92.1.7 (A), TF-1 (B) and K-562 (C) whole cell lysates.

Ankyrin-1 (K-20) - sc-87551 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Ankyrin-1 (K-20): sc-87551. Western blot analysis of Ankyrin-1 expression in non-transfected: sc-117752 (A) and human Ankyrin-1 transfected: sc-371924 (B) 293T whole cell lysates.

Ankyrin-1 (N-13) - sc-87552 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Ankyrin-1 (N-13): sc-87552. Western blot analysis of Ankyrin-1 expression in non-transfected: sc-117752 (A) and human Ankyrin-1 transfected: sc-371924 (B) 293T whole cell lysates.

Anti-ANK1 / Ankyrin Antibody (clone Ank016) - LS-C84787 from LifeSpan Bioscience

Prices $755.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone Ank016

Anti-ANK1 / Ankyrin Antibody (N-Terminus) - LS-C41714 from LifeSpan Bioscience

Prices $345.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-ANK1 / Ankyrin Antibody (aa1-11) - LS-C126796 from LifeSpan Bioscience

Prices $455.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-ANK1 / Ankyrin Antibody (aa1971-1983) - LS-C87265 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ANK1 / Ankyrin Antibody - LS-C309451 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ANK1 / Ankyrin Antibody (aa1831-1881) - LS-C289752 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Detection of Human Ankyrin 1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Ankyrin 1 antibody used for WB at 0.4 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. Ankyrin 1 was also immunoprecipitated by rabbit anti-Ankyrin 1 antibody BL10828, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A and B).

Anti-ANK1 / Ankyrin Antibody (aa863-912) - LS-C107626 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ANK1 antibody LS-C107626 Western blot of HT1080 cell lysate.

Anti-ANK1 / Ankyrin Antibody (C-Terminus) - LS-C31904 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ANK1 antibody LS-C31904 was used in IHC to stain formalin-fixed, paraffin-embedded human lung.

Anti-ANK1 / Ankyrin Antibody (clone 3C3) - LS-C196658 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C3
Immunoprecipitation of ANK1 transfected lysate using anti-ANK1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with ANK1 rabbit polyclonal antibody.

Ankyrin 1 Antibody - NBP2-33806 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Ankyrin 1 Antibody - NBP1-55102 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Ankyrin 1 Antibody [NBP1-55102] - Titration: 0.2-1 ug/ml, Positive Control: HT1080 cell lysate.

Ankyrin 1 Antibody - NBP1-71805 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Ankyrin 1 Antibody - NBP1-90168 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Ankyrin 1 Antibody - NBP1-02311 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Ankyrin 1 Antibody - H00000286-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Ankyrin 1 Antibody [H00000286-D01P] - Analysis of ANK1 expression in transfected 293T cell line by ANK1 polyclonal antibody.Lane 1: ANK1 transfected lysate(17.70 KDa).Lane 2: Non-transfected lysate.

Ankyrin 1 Antibody - H00000286-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

Ankyrin 1 Antibody (3C3) - H00000286-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C3

Ankyrin erythroid Polyclonal Antibody - bs-7594R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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