| Gene Symbol |
Itga5
|
| Entrez Gene |
16402
|
| Alt Symbol |
Cd49e, Fnra, VLA5
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
integrin alpha 5 (fibronectin receptor alpha)
|
| Other Description |
CD49 antigen-like family member E|fibronectin receptor alpha polypeptide|fibronectin receptor subunit alpha|integrin alpha-5|integrin alpha-F
|
| Swissprots |
E9QN40 P11688
|
| Accessions |
EDL03921 EDL03922 P11688 AK142241 AK144921 AK148138 AK152594 BAE31343 AK190883 AK191912 AK192479 AK194064 AK195773 AK196513 AK199283 AK200214 AK200582 AK202968 AK203183 AK204589 AK204695 AK205630 AK211202 AK211262 AK218419 BC050943 AAH50943 BC053431 BC059829 AAH59829 X15203 CAA33273 X79003 CAA55638 NM_010577 NP_034707
|
| Function |
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. May play a role in the survival of adult skeletal muscle.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Proteoglycans in cancer, Hematopoietic cell lineage, MicroRNAs in cancer
|
