| Gene Symbol |
MYCT1
|
| Entrez Gene |
80177
|
| Alt Symbol |
MTLC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myc target 1
|
| Other Description |
myc target in myeloid cells 1|myc target in myeloid cells protein 1|myc target protein 1
|
| Swissprots |
Q9H763 Q8N396 Q8N699 Q8TBE8
|
| Accessions |
EAW47726 Q8N699 AA152372 AF527367 AAM88866 AK021612 AK024922 BAB15035 AL834500 CAD39158 BC022556 AAH22556 BC128463 AAI28464 BC128464 AAI28465 DA863771 GU997693 ADG03644 XM_011536149 XP_011534451 XM_011536150 XP_011534452 XM_011536151 XP_011534453 XM_011536152 XP_011534454 XR_942593 NM_025107 NP_079383
|
| Function |
May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:12673574}. Note=Expressed in nuclei of hepatocellular carcinoma cell line BEL-7402 cells.
|
| Tissue Specificity |
Down-regulated in gastric cancer tissues.
|