Gene Symbol | Pigr |
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Entrez Gene | 25046 |
Alt Symbol | RNPIGR2, pIgA-R |
Species | Rat |
Gene Type | protein-coding |
Description | polymeric immunoglobulin receptor |
Other Description | poly-Ig receptor|polymeric IgA receptor |
Swissprots | P15083 |
Accessions | AAC53400 EDM09843 P15083 FQ104960 L13235 L13296 L14001 L14003 U02506 U07886 X15741 CAA33758 NM_012723 NP_036855 |
Function | This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Top Pathways | Intestinal immune network for IgA production |
PIGR Antibody - abx103493 from Abbexa
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PIGR Antibody - abx103494 from Abbexa
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Anti-Polymeric Immunoglobulin Receptor (PIGR) - 20-3549 from ARP American Research Products
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Anti-Polymeric Immunoglobulin Receptor (PIGR) - 20-3550 from ARP American Research Products
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Polymeric Immunoglobulin Receptor Antibody - abx130184 from Abbexa
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Polymeric Immunoglobulin Receptor (PIGR) Polyclonal Antibody - CAU26551 from Biomatik
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Polymeric Immunoglobulin Receptor (PIGR) Polyclonal Antibody - CAU26552 from Biomatik
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Polymeric Immunoglobulin Receptor (PIGR) Polyclonal Antibody - CAU26553 from Biomatik
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