| Gene Symbol |
ZNHIT1
|
| Entrez Gene |
10467
|
| Alt Symbol |
CG1I, ZNFN4A1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger, HIT-type containing 1
|
| Other Description |
H_DJ0747G18.14|cyclin-G1-binding protein 1|p18 Hamlet|p18Hamlet|putative cyclin G1 interacting protein|zinc finger HIT domain-containing protein 1|zinc finger protein subfamily 4A member 1|zinc finger protein, subfamily 4A (HIT domain containing), member 1|zinc finger, HIT domain containing 1|zinc finger, HIT type 1
|
| Swissprots |
Q6IB12 O43257
|
| Accessions |
AAD45833 EAW50206 EAW50207 EAW50208 EAW50209 O43257 AF093571 AAF03558 AK092478 AK125123 AK312136 BAG35072 BC001877 BC010454 BC017333 AAH17333 CR456992 CAG33273 DQ892275 ABM83201 DQ895476 ABM86402 U61837 AAB88578 XM_011515739 XP_011514041 NM_006349 NP_006340
|
| Function |
Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity. {ECO:0000269|PubMed:17380123, ECO:0000269|PubMed:17892483}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:17892483}.
|
| Tissue Specificity |
Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine. {ECO:0000269|PubMed:17892483}.
|