Gene Symbol | Hnf4a |
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Entrez Gene | 15378 |
Alt Symbol | HNF-4, Hnf4, Hnf4alpha, MODY1, Nr2a1, Tcf14 |
Species | Mouse |
Gene Type | protein-coding |
Description | hepatic nuclear factor 4, alpha |
Other Description | HNF-4-alpha|HNF4 alpha|HNF4alpha10|HNF4alpha11|HNF4alpha12|Nuclear receptor 2A1|TCF-14|hepatocyte nuclear factor 4-alpha|nuclear receptor subfamily 2 group A member 1|transcription factor 14|transcription factor HNF-4 |
Swissprots | Q3UNX3 A2ICH0 P49698 A2A5I5 Q8CFY1 |
Accessions | AAX90602 EDL06336 EDL06337 P49698 AF015275 AAC02906 AK143948 BAE25624 BC024551 BC039220 AAH39220 D29015 BAA06101 EF193391 ABM69089 EF193393 ABM69091 FJ608819 ACM50919 FJ608820 ACM50920 FJ608821 ACM50921 XM_006498787 XP_006498850 XM_006498788 XP_006498851 XM_011239305 XP_011237607 XM_011239306 XP_011237608 NM_008261 NP_032287 |
Function | Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine. |
Subcellular Location | Nucleus. |
Top Pathways | Maturity onset diabetes of the young, AMPK signaling pathway |
HNF-4α CRISPR/Cas9 KO Plasmid (m) - sc-420892 from Santa Cruz Biotechnology
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HNF-4α HDR Plasmid (m) - sc-420892-HDR from Santa Cruz Biotechnology
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HNF-4α Double Nickase Plasmid (m) - sc-420892-NIC from Santa Cruz Biotechnology
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HNF-4α Double Nickase Plasmid (m2) - sc-420892-NIC-2 from Santa Cruz Biotechnology
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HNF-4α CRISPR Activation Plasmid (m) - sc-420892-ACT from Santa Cruz Biotechnology
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HNF-4α CRISPR Activation Plasmid (m2) - sc-420892-ACT-2 from Santa Cruz Biotechnology
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HNF-4α Lentiviral Activation Particles (m) - sc-420892-LAC from Santa Cruz Biotechnology
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HNF-4α Lentiviral Activation Particles (m2) - sc-420892-LAC-2 from Santa Cruz Biotechnology
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HNF-4α siRNA (m) - sc-35574 from Santa Cruz Biotechnology
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HNF-4α shRNA Plasmid (m) - sc-35574-SH from Santa Cruz Biotechnology
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HNF-4α shRNA (m) Lentiviral Particles - sc-35574-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU023811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33362 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33362 from Sigma-Aldrich
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HNF4A siRNA (Mouse) - CRM1864 from Cohesion Biosciences
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HNF4A - MBS8231000 from MyBioSource
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shRNA set against Mouse HNF4A (NM_008261.2) - SHH313645 from Creative biogene
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shRNA set against Mouse Hnf4a(NM_008261.2) - SHH126335 from Creative biogene
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HNF4A shRNA Plasmid (Mouse) - CHM1864 from Cohesion Biosciences
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HNF4A miRNA 3'UTR clone - MiUTR1M-05711 from Creative biogene
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