ENO1

Gene Symbol	ENO1
Entrez Gene	2023
Alt Symbol	ENO1L1, MPB1, NNE, PPH
Species	Human
Gene Type	protein-coding
Description	enolase 1, (alpha)
Other Description	2-phospho-D-glycerate hydro-lyase|MYC promoter-binding protein 1|alpha enolase like 1|alpha-enolase|enolase-alpha|non-neural enolase|phosphopyruvate hydratase|plasminogen-binding protein|tau-crystallin
Swissprots	Q53FT9 B2RD59 Q96GV1 Q7Z3V6 Q71V37 Q8WU71 Q16704 Q4TUS4 Q9UM55 Q9UCH6 Q9BT62 Q658M5 P22712 Q6GMP2 P06733 Q53HR3
Accessions	AAY43128 CAA34360 CBN61326 EAW71604 EAW71605 P06733 AF035286 AAB88178 AK098420 AK222517 BAD96237 AK223192 BAD96912 AK298600 BAH12823 AK309177 AK309291 AK315417 BAG37806 AL833741 CAH56247 AM393606 CAL38482 BC001810 AAH01810 BC004325 AAH04325 BC004458 AAH04458 BC009218 AAH09218 BC009912 AAH09912 BC011130 AAH11130 BC015641 AAH15641 BC021166 AAH21166 BC022545 AAH22545 BC027725 AAH27725 BC050642 AAH50642 BC113034 AAI13035 BT007163 AAP35827 BX537400 CAD97642 D28437 BAA05803 DQ891441 ABM82367 DQ894619 ABM85545 EF036495 ABO65081 GU170215 ADK47995 M14328 AAA52387 M55914 AAA35698 X84907 CAA59331 XM_006710433 XP_006710496 NM_001201483 NP_001188412 NM_001428 NP_001419
Function	Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:10802057}. Cell membrane {ECO:0000269|PubMed:10802057}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000269|PubMed:10802057}. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M line.
Tissue Specificity	The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Top Pathways	Glycolysis / Gluconeogenesis, RNA degradation, Biosynthesis of amino acids, Carbon metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Non Neuronal Enolase full length protein - ab167976 from Abcam Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

ENO1 full length protein - ab138347 from Abcam Category Protein Prices $1,199.00 Sizes 1 mg Source E. coli

Human ENO1 full length protein - ab89248 from Abcam Category Protein Source E. coli Species Human

Human ENO1 full length protein - ab88286 from Abcam Category Protein Source Saccharomyces cerevisiae Species Human

Human Non Neuronal Enolase peptide - ab98944 from Abcam Category Peptide

ENO1 / Alpha Enolase Antibody Blocking Peptide - LS-E12177 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ENO1 / Alpha Enolase Antibody Blocking Peptide - LS-E12178 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ENO1 / Alpha Enolase Antibody Blocking Peptide - LS-E8263 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Enolase 1 Protein - H00002023-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Enolase 1 Partial Recombinant Protein - H00002023-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Enolase 1 Recombinant Protein - H00002023-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Enolase 1 Protein - NBP1-30262 from Novus Biologicals Category Protein Prices $279.00, $629.00 Sizes 100 µg, 500 µg Source E.coli Species Human

ENOA-Antibody-N-term-Blocking-Peptide - BP2879a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ENO1-Antibody-Center-Blocking-Peptide - BP6526c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ENO1-Antibody-N-term-Blocking-Peptide - BP6526a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Non-Neuronal Enolase Protein (OPMA04319) - OPMA04319 from Aviva Systems Biology Category Protein Prices $755.00 Sizes 100 µg Source Human brain

ENO1 Protein (OPPA01968) - OPPA01968 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human ENO1 protein - orb245127 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

NNE protein - orb79678 from Biorbyt Category Protein Prices $680.00, $1,284.00, $1,666.00 Sizes 100 µg, 500 µg, 1 mg

Human Enolase-1 protein - orb90084 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Source E.coli

alpha Enolase protein - 30-1375 from Fitzgerald Category Protein Prices $335.00 Sizes 500 µg Source E.coli

Alphaenolase protein - 30R-1404 from Fitzgerald Category Protein Prices $295.00 Sizes 100 µg Source E.coli

C. Albicans eno1 protein (His tag) - 80-1341 from Fitzgerald Category Protein Prices $195.00, $895.00 Sizes 100 µg, 1 mg Source E.coli

NNE protein - 30R-AN007 from Fitzgerald Category Protein Prices $195.00 Sizes 100 µg

Human ENOA Protein - abx060054 from Abbexa Category Protein Source Yeast Species Human

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