LIAS

Gene Symbol LIAS
Entrez Gene 11019
Alt Symbol HUSSY-01, LAS, LIP1, LS, PDHLD
Species Human
Gene Type protein-coding
Description lipoic acid synthetase
Other Description LS|lip-syn|lipoate synthase|lipoyl synthase, mitochondrial
Swissprots Q8IV62 C9JCF6 O43766 A8K873
Accessions CBN72404 CBN72413 EAW92932 EAW92933 EAW92934 O43766 AI373464 AJ224162 CAA11859 AK026289 AK291985 BAF84674 AK292238 BAF84927 AK303429 BAG64479 AL528262 AV729111 BC023635 AAH23635 BC062751 AAH62751 BF434814 HQ447772 ADQ32257 XM_006713990 XP_006714053 NM_001278590 NP_001265519 NM_001278591 NP_001265520 NM_001278592 NP_001265521 NM_006859 NP_006850 NM_194451 NP_919433
Function Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000255|HAMAP-Rule:MF_03123}.
Subcellular Location Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03123}.
Top Pathways Lipoic acid metabolism

Panoply™ Human LIAS Knockdown Stable Cell Line - CSC-DC008694 from Creative biogene

Category Cell Line
Species Human
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