| Gene Symbol |
DSCAML1
|
| Entrez Gene |
57453
|
| Alt Symbol |
DSCAM2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Down syndrome cell adhesion molecule like 1
|
| Other Description |
DSCAM-like 1|Down syndrome cell adhesion molecule-like protein 1|Downs syndrome cell adhesion molecule like 1|down syndrome cell adhesion molecule 2
|
| Swissprots |
Q9ULT7 Q8TD84 Q76MU9 Q8WXU7 Q8IZY4 Q8IZY3
|
| Accessions |
EAW67322 EAW67323 Q8TD84 AB032958 BAA86446 AF304304 AAN32613 AF304305 AAN32614 AF334384 AAL57166 AF491813 AAM09558 AK025940 BC156376 AAI56377 BM665756 XM_011542917 XP_011541219 XM_011542918 XP_011541220 XM_011542919 XP_011541221 XM_011542920 XP_011541222 XM_011542921 XP_011541223 XM_011542922 XP_011541224 XM_011542923 XP_011541225 XM_011542924 XP_011541226 XM_011542925 XP_011541227 NM_020693 NP_065744
|
| Function |
Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus. {ECO:0000269|PubMed:11453658, ECO:0000269|PubMed:12051741}.
|