DDX3X

Gene Symbol DDX3X
Entrez Gene 1654
Alt Symbol CAP-Rf, DBX, DDX14, DDX3, HLP2
Species Human
Gene Type protein-coding
Description DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
Other Description ATP-dependent RNA helicase DDX3X|DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked|DEAD box protein 3, X-chromosomal|DEAD box, X isoform|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3|DEAD/H box-3|helicase-like protein 2
Swissprots O15536 O00571 B4E3E8 A8K538
Accessions EAW59402 EAW59403 EAW59404 EAW59405 O00571 AA481139 AB208983 BAD92220 AB451220 BAG70034 AB451343 BAG70157 AF000982 AAC51829 AF000983 AAC51830 AF061337 AAC34298 AF086430 AI698207 AK127902 AK291153 BAF83842 AK296906 BAG59462 AK297159 BAG59657 AK304661 BAG65436 AK304689 BAG65460 AK310891 AU144400 AY776161 AAV52794 BC007668 BC011819 AAH11819 BC055083 BF980241 BM454841 BM833870 BQ921695 CB107740 DA232063 DB065845 L37696 U50553 AAB95637 XM_011543892 XP_011542194 NM_001193416 NP_001180345 NM_001193417 NP_001180346 NM_001356 NP_001347 NR_126093 NR_126094 NM_024005
Function Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo- and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5'- single-stranded DNA overhangs. Is involved in several steps of gene expression, such as transcription, mRNA maturation, mRNA export and translation. However, the exact mechanisms are not known and some functions may be specific for a subset of mRNAs. Involved in transcriptional regulation. Can enhance transcription from the CDKN1A/WAF1 promoter in a SP1-dependent manner. Found associated with the E-cadherin promoter and can down-regulate transcription from the promoter. Involved in regulation of translation initiation. Proposed to be involved in positive regulation of translation such as of cyclin E1/CCNE1 mRNA and specifically of mRNAs containing complex secondary structures in their 5'UTRs; these functions seem to require RNA helicase activit
Subcellular Location Nucleus speckle. Cytoplasm. Mitochondrion outer membrane. Note=Located predominantly in nuclear speckles and, at low levels, throughout the cytoplasm. Located to the outer side of nuclear pore complexes (NPC). Shuttles between the nucleus and the cytoplasm in a XPO1 and may be also in a NFX1-dependent manner. Associated with polyadenylated mRNAs in the cytoplasm and the nucleus. Predominantly located in nucleus during G(0) phase and in the cytoplasm during G1/S phase.
Top Pathways RIG-I-like receptor signaling pathway, Viral carcinogenesis

Mouse/Human/Rat DDX3 / DDX3X ELISA Kit (Cell-Based ELISA) - LS-F1940 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

ATP-dependent RNA helicase DDX3X (DDX3X), Human, ELISA Kit - E01A1832 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 2.5-50ng/ml

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7219470 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7248921 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7206959 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7241777 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7221053 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7244364 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7220337 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7253365 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7252086 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7212455 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7250625 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DDX3 Colorimetric Cell-Based ELISA Kit - CB5202 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

ATP dependent RNA helicase DDX3X (DDX3X), ELISA Kit - MBS7235175 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DDX3 ELISA Kit - DEIA-XYA538 from Creative Diagnostics

Category ELISA Kit

Human DDX3X ELISA Kit - E004032 from Biobool

Category ELISA Kit

anti-DDX3 antibody - ARG54169 from Arigo Biolaboratories

Category ELISA Kit

DDX3 Colorimetric Cell-Based ELISA Kit - EKA50175 from Biomatik

Category ELISA Kit
Prices $399.00
Sizes 96 tests
Sensitivity At least 5000 cells/well
Range Qualitative
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