| Gene Symbol |
GP5
|
| Entrez Gene |
2814
|
| Alt Symbol |
CD42d, GPV
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glycoprotein V (platelet)
|
| Other Description |
glycoprotein 5|platelet glycoprotein V
|
| Swissprots |
P40197 D1MER9
|
| Accessions |
ACZ44929 CAA80637 CBX54456 CDI44163 EAW78053 P40197 BC152810 AAI52811 L11238 AAA03069 NM_004488 NP_004479
|
| Function |
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Platelets and megakaryocytes.
|
| Top Pathways |
ECM-receptor interaction, Hematopoietic cell lineage
|