ANK3

Gene Symbol ANK3
Entrez Gene 288
Alt Symbol ANKYRIN-G, MRT37
Species Human
Gene Type protein-coding
Description ankyrin 3, node of Ranvier (ankyrin G)
Other Description ankyrin G119|ankyrin-3
Swissprots Q13484 Q12955 Q9H0P5 Q7Z3G4 Q5CZH9 B1AQT2 B4DIL1 Q5VXD5 E9PE32
Accessions EAW54199 EAW54200 EAW54201 EAW54202 Q12955 AB209308 BAD92545 AK092361 BAG52538 AK092527 BAC03910 AK124230 BAG54022 AK126851 BAC86721 AK128763 AK128784 AK172736 AK292927 BAF85616 AK295661 BAG58523 AL136710 CAB66645 AW451432 BG427669 BP216034 BP245303 BX537917 CAD97900 BX648574 CAI56716 EF139850 EF139851 EU832293 ACE87550 EU832377 ACE86862 U13616 AAA64834 XM_005269715 XP_005269772 XM_005269716 XP_005269773 XM_006717791 XP_006717854 XM_006717793 XP_006717856 XM_006717795 XP_006717858 XM_006717796 XP_006717859 XM_006717802 XP_006717865 XM_011539700 XP_011538002 XM_011539701 XP_011538003 XM_011539702 XP_011538004 XM_011539703 XP_011538005 XM_011539704 XP_011538006 XM_011539705 XP_011538007 XM_011539706 XP_011538008 XM_011539707 XP_011538009 XM_011539708 XP_011538010 XM_011539709 XP_011538011 XM_011539710 XP_011538012 XM_011539711 XP_011538013 XM_011539712 XP_011538014 XM_011539713 XP_011538015 XM_011539714 XP_011538016 XM_011539715 XP_011538017 XM_011539716 XP_011538018 XM_011539717 XP_011538019 XM_011539718 XP_011538020 XM_011539719 XP_011538021 NM_001149 NP_001140 NM_001204403 NP_001191332 NM_001204404 NP_001191333 NM_020987 NP_066267
Function In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption (PubMed:23903368). {ECO:0000250, ECO:0000269|PubMed:17974005}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21223964}. Cell projection, axon {ECO:0000250}. Cell membrane, sarcolemma {ECO:0000269|PubMed:21223964}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Lysosome {ECO:0000250}. Note=In skeletal muscle, localized at costameres and neuromuscular junctions. In macrophages, associated with lysosomes. {ECO:0000250}.
Tissue Specificity Expressed in brain, neurons, muscles and other tissues. {ECO:0000269|PubMed:21223964, ECO:0000269|PubMed:7836469}.
Top Pathways Proteoglycans in cancer

Ankyrin G CRISPR/Cas9 KO Plasmid (h) - sc-400421 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ankyrin G HDR Plasmid (h) - sc-400421-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ankyrin G Double Nickase Plasmid (h) - sc-400421-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ankyrin G Double Nickase Plasmid (h2) - sc-400421-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ankyrin G CRISPR Activation Plasmid (h) - sc-400421-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ankyrin G CRISPR Activation Plasmid (h2) - sc-400421-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ankyrin G Lentiviral Activation Particles (h) - sc-400421-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ankyrin G Lentiviral Activation Particles (h2) - sc-400421-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ankyrin G siRNA (h) - sc-43263 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Ankyrin G shRNA Plasmid (h) - sc-43263-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Ankyrin G shRNA (h) Lentiviral Particles - sc-43263-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EHU093441 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3157 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3157 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ANK3 siRNA (Human) - CRH0201 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ANK3 - MBS827671 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Ank3 (NM_001149.3) - SHH236366 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ANK3(NM_001204403.1) - SHG058717 from Creative biogene

Category siRNA
Species Reactivities Human

Human ANK3 siRNA - orb260703 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ANK3 shRNA Plasmid (Human) - CHH0201 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ANK3 miRNA 3'UTR clone - MiUTR1H-00372 from Creative biogene

Species Reactivities Human

ANK3 miRNA 3'UTR clone - MiUTR1H-00373 from Creative biogene

Species Reactivities Human

ANK3 miRNA 3'UTR clone - MiUTR1H-00374 from Creative biogene

Species Reactivities Human

ANK3 miRNA 3'UTR clone - MiUTR3H-03392 from Creative biogene

Species Reactivities Human
Search more