Gene Symbol | Arpc4 |
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Entrez Gene | 68089 |
Alt Symbol | 20kDa, 5330419I20Rik, AI327076, p20-Arc |
Species | Mouse |
Gene Type | protein-coding |
Description | actin related protein 2/3 complex, subunit 4 |
Other Description | actin-related protein 2/3 complex subunit 4|arp2/3 complex 20 kDa subunit |
Swissprots | Q3UWV4 P59999 |
Accessions | EDK99458 EDK99459 P59999 AJ278129 CAC34583 AK003923 AK017993 BAB31026 AK018069 BAB31059 AK030840 AK039215 BAC30279 AK076248 BAC36272 AK077325 BAC36751 AK133626 BAE21755 AK136082 BAE22810 AK150690 BAE29769 AK153380 BAE31946 AK159410 BAE35061 AK166440 BAE38777 AK193553 AK194624 AK194784 AK196019 AK196451 AK197517 AK202031 BC015280 BC055309 AAH55309 NM_001170485 NP_001163956 NM_001170486 NP_001163957 NM_026552 NP_080828 |
Function | Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection {ECO:0000250}. |
Top Pathways | Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton |
p20-ARC CRISPR/Cas9 KO Plasmid (m) - sc-426917 from Santa Cruz Biotechnology
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p20-ARC HDR Plasmid (m) - sc-426917-HDR from Santa Cruz Biotechnology
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p20-ARC Double Nickase Plasmid (m) - sc-426917-NIC from Santa Cruz Biotechnology
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p20-ARC Double Nickase Plasmid (m2) - sc-426917-NIC-2 from Santa Cruz Biotechnology
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p20-ARC CRISPR Activation Plasmid (m) - sc-426917-ACT from Santa Cruz Biotechnology
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p20-ARC CRISPR Activation Plasmid (m2) - sc-426917-ACT-2 from Santa Cruz Biotechnology
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p20-ARC Lentiviral Activation Particles (m) - sc-426917-LAC from Santa Cruz Biotechnology
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p20-ARC Lentiviral Activation Particles (m2) - sc-426917-LAC-2 from Santa Cruz Biotechnology
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p20-ARC siRNA (m) - sc-155923 from Santa Cruz Biotechnology
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p20-ARC shRNA Plasmid (m) - sc-155923-SH from Santa Cruz Biotechnology
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p20-ARC shRNA (m) Lentiviral Particles - sc-155923-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU147741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN27033 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27033 from Sigma-Aldrich
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ARPC4 siRNA (Mouse) - CRM7510 from Cohesion Biosciences
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ARPC4 - MBS8223956 from MyBioSource
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shRNA set against Mouse ARPC4 (NM_026552.3) - SHH240658 from Creative biogene
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Mouse ARPC4 siRNA - orb286986 from Biorbyt
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ARPC4 shRNA Plasmid (Mouse) - CHM7510 from Cohesion Biosciences
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