| Gene Symbol |
SLC26A3
|
| Entrez Gene |
1811
|
| Alt Symbol |
CLD, DRA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 26 (anion exchanger), member 3
|
| Other Description |
chloride anion exchanger|down-regulated in adenoma protein|solute carrier family 26, member 3
|
| Swissprots |
P40879
|
| Accessions |
AAB88772 EAW83418 EAW83419 EAW83420 P40879 AK300651 BAG62339 BC025671 AAH25671 BP262081 BX640837 CAE45910 DQ891550 ABM82476 EU176616 ABW03417 L02785 AAA58443 XM_011515867 XP_011514169 NM_000111 NP_000102
|
| Function |
Chloride/bicarbonate exchanger. Mediates the efficient absorption of chloride ions in the colon, participating in fluid homeostasis. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
|
| Subcellular Location |
Apical cell membrane {ECO:0000269|PubMed:22159084}; Multi-pass membrane protein {ECO:0000269|PubMed:22159084}. Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Localized in sperm membranes. Midpiece of sperm tail. Colocalizes with CFTR at the midpiece of sperm tail (By similarity). {ECO:0000250}.
|
| Top Pathways |
Pancreatic secretion, Mineral absorption
|