Polr1b

Gene Symbol Polr1b
Entrez Gene 20017
Alt Symbol 128kDa, D630020H17Rik, RPA116, RPA135, RPA2, Rpo1-2
Species Mouse
Gene Type protein-coding
Description polymerase (RNA) I polypeptide B
Other Description DNA-directed RNA polymerase I 135 kDa polypeptide|DNA-directed RNA polymerase I 135kDa polypeptide|DNA-directed RNA polymerase I subunit RPA2|RNA polymerase 1-2, 128 kDa subunit|RNA polymerase I subunit 2
Swissprots Q3UMX7 P70700
Accessions EDL28227 P70700 AK052672 AK083732 AK143501 BAE25401 AK144616 BAE25971 AK156712 AK197463 BB860575 BC060656 AAH60656 U58280 AAC52850 XM_006499025 XP_006499088 XM_006499026 XP_006499089 XR_374430 NM_009086 NP_033112
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). {ECO:0000250}.
Subcellular Location Nucleus, nucleolus {ECO:0000250}.
Top Pathways Purine metabolism, RNA polymerase, Pyrimidine metabolism

RPA135 CRISPR/Cas9 KO Plasmid (m) - sc-422729 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RPA135 HDR Plasmid (m) - sc-422729-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RPA135 Double Nickase Plasmid (m) - sc-422729-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RPA135 Double Nickase Plasmid (m2) - sc-422729-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RPA135 CRISPR Activation Plasmid (m) - sc-422729-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RPA135 CRISPR Activation Plasmid (m2) - sc-422729-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RPA135 Lentiviral Activation Particles (m) - sc-422729-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RPA135 Lentiviral Activation Particles (m2) - sc-422729-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RPA135 siRNA (m) - sc-36437 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

RPA135 shRNA Plasmid (m) - sc-36437-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

RPA135 shRNA (m) Lentiviral Particles - sc-36437-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU054771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN39030 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND39030 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

POLR1B siRNA (Mouse) - CRM3531 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse POLR1B (NM_009086.2) - SHH379336 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse POLR1B siRNA - orb283007 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

POLR1B shRNA Plasmid (Mouse) - CHM3531 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
Search more