Gene Symbol | MPHOSPH6 |
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Entrez Gene | 10200 |
Alt Symbol | MPP, MPP-6, MPP6 |
Species | Human |
Gene Type | protein-coding |
Description | M-phase phosphoprotein 6 |
Other Description | - |
Swissprots | Q99547 B2RAF0 |
Accessions | EAW95516 EAW95517 EAW95518 Q99547 AI831131 AK222667 BAD96387 AK314163 BAG36847 AW175781 BC005242 AAH05242 BC011020 AAH11020 BC029395 AAH29395 BC031017 AAH31017 BU595100 BU622913 HQ447909 ADQ32393 X98263 CAA66916 XM_011522808 XP_011521110 NM_005792 NP_005783 |
Function | RNA-binding protein that associates with the RNA exosome complex. Involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and may play a role in recruiting the RNA exosome complex to pre-rRNA; this function may include C1D. {ECO:0000269|PubMed:17412707}. |
Subcellular Location | Nucleus, nucleolus. Cytoplasm. Note=Cytoplasmic in M phase. |
Top Pathways | RNA degradation |
MPP6 CRISPR/Cas9 KO Plasmid (h) - sc-411432 from Santa Cruz Biotechnology
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MPP6 HDR Plasmid (h) - sc-411432-HDR from Santa Cruz Biotechnology
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MPP6 Double Nickase Plasmid (h) - sc-411432-NIC from Santa Cruz Biotechnology
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MPP6 Double Nickase Plasmid (h2) - sc-411432-NIC-2 from Santa Cruz Biotechnology
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MPP6 CRISPR Activation Plasmid (h) - sc-411432-ACT from Santa Cruz Biotechnology
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MPP6 CRISPR Activation Plasmid (h2) - sc-411432-ACT-2 from Santa Cruz Biotechnology
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MPP6 Lentiviral Activation Particles (h) - sc-411432-LAC from Santa Cruz Biotechnology
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MPP6 Lentiviral Activation Particles (h2) - sc-411432-LAC-2 from Santa Cruz Biotechnology
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MPHOSPH6 siRNA (h) - sc-62635 from Santa Cruz Biotechnology
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MPHOSPH6 shRNA Plasmid (h) - sc-62635-SH from Santa Cruz Biotechnology
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MPHOSPH6 shRNA (h) Lentiviral Particles - sc-62635-V from Santa Cruz Biotechnology
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MPHOSPH6 RNAi - H00010200-R01 from Novus Biologicals
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MISSION® esiRNA - EHU019451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14496 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14496 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05568 from Sigma-Aldrich
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MPHOSPH6 siRNA (Human) - CRH6889 from Cohesion Biosciences
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shRNA set against Human MPHOSPH6 (NM_005792.2) - SHH343840 from Creative biogene
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shRNA set against Human MPHOSPH6(NM_005792.2) - SHH196823 from Creative biogene
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Human MPHOSPH6 siRNA - orb267391 from Biorbyt
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MPHOSPH6 shRNA Plasmid (Human) - CHH6889 from Cohesion Biosciences
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MPHOSPH6 miRNA 3'UTR clone - MiUTR1H-06394 from Creative biogene
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