| Gene Symbol |
Chrnb2
|
| Entrez Gene |
11444
|
| Alt Symbol |
Acrb-2, Acrb2, C030030P04Rik, [b]2-nAchR
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
|
| Other Description |
acetylcholine receptor beta 2 neural|neuronal acetylcholine receptor subunit beta-2
|
| Swissprots |
Q9ERK7 Q8BGP7
|
| Accessions |
AAD44476 CAA57978 EDL15184 Q9ERK7 AF089739 AAD44504 AF145286 AAD33069 AF299083 AAG23697 AF325349 AAL37365 AK049722 BAC33893 AK051742 BAC34749 AK081254 AY574267 AAS90363 BC065103 AAH65103 BY123599 NM_009602 NP_033732
|
| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions. {ECO:0000250}.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Nicotine addiction, Neuroactive ligand-receptor interaction
|