CSF3R

Gene Symbol CSF3R
Entrez Gene 1441
Alt Symbol CD114, GCSFR
Species Human
Gene Type protein-coding
Description colony stimulating factor 3 receptor (granulocyte)
Other Description CD114 antigen|G-CSF receptor|G-CSF-R|granulocyte colony-stimulating factor receptor
Swissprots Q99062
Accessions AAB20660 AAB34956 AAD14994 AAN05790 EAX07354 EAX07355 EAX07356 EAX07357 EAX07358 Q99062 AB209656 BAD92893 AK307242 BC040954 BC053585 AAH53585 BI912247 BU681211 BX370109 DA858302 DQ424902 ABD83667 M59818 AAA63176 M59819 AAA63177 M59820 AAA63178 X55720 CAA39252 X55721 CAA39253 XM_005270493 XP_005270550 XM_011540748 XP_011539050 XM_011540749 XP_011539051 XM_011540750 XP_011539052 NM_000760 NP_000751 NM_156039 NP_724781 NM_172313 NP_758519 NM_156038
Function Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. {ECO:0000269|PubMed:7514305}.
Subcellular Location Isoform 2: Secreted {ECO:0000305}.
Tissue Specificity One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway

Active human GCSF Receptor protein fragment - ab168697 from Abcam

Category Protein
Prices $352.00
Sizes 100 µg
Source HEK 293 cells
Species Human
SDS PAGE analysis of ab168697 under reducing conditions and stained overnight with Coomassie Blue.

GCSF Receptor protein (Fc Chimera Active) - ab83994 from Abcam

Category Protein
Prices $525.00, $568.00
Sizes 25 µg, 50 µg
Source HEK 293 cells
Species Human
1D SDS-PAGE of ab83994 before and after treatment with glycosidases to remove oligosaccharides. Lane 1: ab83994 Lane 2: ab83994 treated with PNGase F to remove potential N-linked glycans Lane 3: ab83994 treated with a glycosidase cocktail to remove potential N- and O-linked glycans. Approximately 5 µg of protein was loaded per lane; Gel was stained using Coomassie. Drop in MW after treatment with PNGase F indicates presence of N-linked glycans. A tightening of the band after treatment with the glycosidase cocktail indicates that O-linked glycans may be present. Additional bands in lane 2 and lane 3 are glycosidase enzymes.

Human GCSF Receptor protein fragment - ab158213 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158213 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CSF3R / CD114 Antibody Blocking Peptide - LS-E9925 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CSF3R / CD114 Antibody Blocking Peptide - LS-E27966 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

G-CSF R/CD114 Partial Recombinant Protein - H00001441-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human G-CSF R/CD114 Protein - H00001441-G01 from Novus Biologicals

Category Protein
Prices $569.00
Sizes 10 µg
Source Wheat Germ
Species Human

CSF3R-Antibody-Center-Blocking-Peptide - BP9075c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human G-CSF R/CD114 - 381-GR-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Glu25-Pro621

Recombinant Human G-CSF R/CD114, CF - 381-GR-050/CF from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Glu25-Pro621

Recombinant human Granulocyte colony-stimulating factor receptor (OPCA00891) - OPCA00891 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

Human CD114 protein - orb138343 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 50 μg, 100 μg
Source Human Cells
Species Human
SDS-PAGE analysis of human CD114 protein

Human GCSFR Protein - abx066036 from Abbexa

Category Protein
Source E.coli
Species Human

Human GCSFR Protein - abx066037 from Abbexa

Category Protein
Source E.coli
Species Human

CD114 / CSF3R - H00001441-G01 from Acris Antibodies

Category Protein
Prices $550.00
Sizes 10 µg
Species Human

CD114 / CSF3R - H00001441-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

CD114 / CSF3R - H00001441-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Colony Stimulating Factor Receptor Granulocyte - 20-7743 from ARP American Research Products

Category Protein
Prices $419.00
Sizes 50 µg
Source E.coli
Species Human

Colony Stimulating Factor Receptor Granulocyte - 20-7744 from ARP American Research Products

Category Protein
Prices $419.00
Sizes 50 µg
Source E.coli
Species Human

CSF3R Peptide - 43-097P from ProSci

Category Peptide

GCSFR Recombinant Protein - 96-342 from ProSci

Category Protein
Prices $375.00
Sizes 100 µg
Source HEK293 cells
Species Human
The purity of rh GCSFR was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

GCSFR Recombinant Protein - 96-343 from ProSci

Category Protein
Prices $400.00
Sizes 200 µg
Source HEK293 cells
Species Human
The purity of rh G-CSFR Fc Chimera was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

G-CSF-R fusion protein - Ag5848 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

G-CSF-R fusion protein - Ag5992 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human CSF3R, His tagged - CSF3R-5175H from Creative Biomart

Category Protein
Source Human Cells
Species Human
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