| Gene Symbol |
CIRH1A
|
| Entrez Gene |
84916
|
| Alt Symbol |
CIRHIN, NAIC, TEX292, UTP4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cirrhosis, autosomal recessive 1A (cirhin)
|
| Other Description |
UTP4, small subunit (SSU) processome component, homolog|cirhin|testis expressed gene 292
|
| Swissprots |
Q969X6 Q96T13 Q8NCD9 Q9BWK6 Q96SR9 Q8TF14 Q96SZ9 Q96SP0
|
| Accessions |
CCO13709 EAW83251 EAW83252 EAW83253 EAW83254 EAW83255 EAW83256 EAW83257 Q969X6 AB075868 BAB85574 AK027419 BAB55100 AK027445 BAB55116 AK027584 BAB55212 AK027634 BAB55251 AK027675 BAB55287 AK074795 BAC11214 AK310104 BC000167 AAH00167 BC009348 AAH09348 BX647265 CA430627 DA277545 XM_005256204 XP_005256261 XM_005256205 XP_005256262 NM_032830 NP_116219
|
| Function |
May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5'-GGGACTTTCC-3' found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV. Ribosome biogenesis factor involved in small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b. {ECO:0000269|PubMed:19732766, ECO:0000269|PubMed:22916032}.
|
| Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:16225863}.
|
| Top Pathways |
Ribosome biogenesis in eukaryotes
|