GBA

Gene Symbol GBA
Entrez Gene 2629
Alt Symbol GBA1, GCB, GLUC
Species Human
Gene Type protein-coding
Description glucosidase, beta, acid
Other Description D-glucosyl-N-acylsphingosine glucohydrolase|acid beta-glucosidase|alglucerase|beta-GC|beta-glucocerebrosidase|glucosylceramidase|glucosylceramidase-like protein|imiglucerase|lysosomal glucocerebrosidase
Swissprots Q16545 B7Z6S1 J3KQK9 A8K796 Q9UMJ8 J3KQG4 Q4VX22 Q6I9R6 B7Z5G2 P04062
Accessions AAA35874 AAA35875 AAA35876 AAA35878 AAA35879 AAC51820 AAC63056 EAW53100 EAW53101 EAW53102 EAW53103 P04062 AK291911 BAF84600 AK298900 BAH12898 AK300186 BAH13232 AK300829 BAH13357 AK300876 BAH13365 AK301374 BAH13467 AK301879 BAH13574 AK302000 BAH13605 AK311242 AK312502 BAG35404 AL547558 AU122729 AU131071 AU140959 AU141794 BC003356 AAH03356 BI458641 BX382279 BX477204 BX648487 D13286 BAA02545 DC297079 K02920 AAA35877 KJ690771 AID60277 KJ690772 AID60278 KJ690773 AID60279 M16328 AAA35873 M19285 AAA35880 M22212 XM_006711270 XP_006711333 XM_006726211 XP_006726274 XM_011509407 XP_011507709 XM_011546930 XP_011545232 NM_000157 NP_000148 NM_001005741 NP_001005741 NM_001005742 NP_001005742 NM_001171811 NP_001165282 NM_001171812 NP_001165283 NM_001005749 NM_001005750
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}; Peripheral membrane protein {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}; Lumenal side {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}. Note=Interaction with saposin-C promotes membrane association. Targeting to lysosomes occurs through an alternative MPR-independent mechanism via SCARB2.
Top Pathways Lysosome, Sphingolipid metabolism, Other glycan degradation

β-glucosidase (H-300) - sc-32883 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
β-glucosidase (H-300): sc-32883. Western blot analysis of β-glucosidase expression in non-transfected: sc-117752 (A) and human β-glucosidase transfected: sc-110483 (B) 293T whole cell lysates.

β-glucosidase (L-17) - sc-30845 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

β-glucosidase (B-6) - sc-166407 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
β-glucosidase (B-6): sc-166407. Western blot analysis of β-glucosidase expression in non-transfected: sc-117752 (A) and human β-glucosidase transfected: sc-110483 (B) 293T whole cell lysates.

β-glucosidase (N-17) - sc-30844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β-glucosidase (N-17): sc-30844. Western blot analysis of β-glucosidase expression in non-transfected: sc-117752 (A) and human β-glucosidase transfected: sc-110483 (B) 293T whole cell lysates.

β-glucosidase (A-16) - sc-100544 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
β-glucosidase (A-16): sc-100544. Western blot analysis of β-glucosidase expression in non-transfected 293T: sc-117752 (A), human β-glucosidase transfected 293T: sc-110483 (B) and MCF7 (C) whole cell lysates.

Anti-GBA antibody - ab55080 from Abcam

Prices $398.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
GBA antibody (ab55080) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human breast cancer.

Anti-GBA antibody - ab88300 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-GBA antibody (ab88300) at 1 µg/ml + U-2 OS cell lysate at 50 µgdeveloped using the ECL technique

Anti-GBA antibody [EPR5142] - ab125065 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5142
ab125065, at a 1/50 dilution, staining GBA in paraffin-embedded Human colon tissue by immunohistochemistry.

Anti-GBA antibody [EPR5143(3)] - ab128879 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5143(3)

Anti-GBA / Glucosidase Beta Acid Antibody (aa1-536) - LS-C129222 from LifeSpan Bioscience

Prices $445.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (Internal, AP) - LS-C219460 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (Internal, APC) - LS-C219462 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (Internal, Biotin) - LS-C219463 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (C-Terminus) - LS-C145333 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GBA antibody LS-C145333 Western blot of 435S Cell lysate. Antibody concentration 1 ug/ml.

Anti-GBA / Glucosidase Beta Acid Antibody (Internal, FITC) - LS-C219464 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (aa65-384) - LS-C186344 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Hepatoma using GBA antibody at 1:500 dilution.

Anti-GBA / Glucosidase Beta Acid Antibody (Internal, PE) - LS-C219466 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (aa337-365) - LS-C157766 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
GC Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The GC antibody detected the GC protein (arrow).

Anti-GBA / Glucosidase Beta Acid Antibody (Internal, clone EPR5142) - LS-C138437 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5142
IHC of paraffin-embedded human colon tissue using anti-Glucosylceramidase antibody.

Anti-GBA / Glucosidase Beta Acid Antibody (aa117-214, Biotin) - LS-C298413 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (aa248-508, Biotin) - LS-C298656 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (aa334-498, Biotin) - LS-C300135 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (aa255-509, Biotin) - LS-C299956 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (aa334-498, FITC) - LS-C302050 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GBA / Glucosidase Beta Acid Antibody (aa255-509, FITC) - LS-C302526 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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