| Gene Symbol |
Ogdh
|
| Entrez Gene |
18293
|
| Alt Symbol |
2210403E04Rik, 2210412K19Rik, AA409584, d1401, mKIAA4192
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
|
| Other Description |
2-oxoglutarate dehydrogenase complex component E1|2-oxoglutarate dehydrogenase, mitochondrial|OGDC-E1|alpha-ketoglutarate dehydrogenase|oxoglutarate dehydrogenase (lipoamide)
|
| Swissprots |
Q5SVX7 Q80Y57 Q5DTI4 Q60597 Q3UDM7 Q91WP2 Q8R3M2 Q8K2Z3 Q5SVX9 Q6PFZ2 Q8K0K7
|
| Accessions |
EDL40581 EDL40582 EDL40583 EDL40584 EDL40585 EDL40586 Q60597 AK008811 AK075848 AK088779 AK147289 BAE27824 AK150009 BAE29234 AK155856 AK169286 BAE41044 AK180402 AK180571 AK181416 AK183886 AK188421 AK189839 AK189909 AK190396 AK190496 AK190973 AK191182 AK191865 AK193320 AK193717 AK194115 AK195097 AK195375 AK195603 AK196688 AK199209 AK199903 AK201619 AK201981 AK202141 AK202346 AK203647 AK204071 AK204207 AK204256 AK204960 AK213993 AK216535 AK217150 AK219443 AK220536 BAD90530 BC012042 BC013670 AAH13670 BC025040 AAH25040 BC029143 AAH29143 BC031165 AAH31165 BC049104 AAH49104 BC057354 AAH57354 BC061232 AAH61232 BY768178 BY782774 BY785860 U02971 AAC52130 XM_006514582 XP_006514645 XM_006514583 XP_006514646 XM_006514584 XP_006514647 XM_006514585 XP_006514648 XM_006514586 XP_006514649 NM_001252282 NP_001239211 NM_001252283 NP_001239212 NM_001252287 NP_001239216 NM_001252288 NP_001239217 NM_010956 NP_035086
|
| Function |
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
|
| Subcellular Location |
Mitochondrion matrix.
|
| Top Pathways |
Citrate cycle (TCA cycle), Lysine degradation, Tryptophan metabolism, Carbon metabolism
|