Gene Symbol |
Tgfa
|
Entrez Gene |
24827
|
Alt Symbol |
RATTGFAA, TGFAA
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
transforming growth factor alpha
|
Other Description |
protransforming growth factor alpha
|
Swissprots |
Q63749 P01134
|
Accessions |
EDL91222 EDL91223 EDL91224 P01134 KF366251 AGX26150 M31076 AAA42233 X02004 CAA26036 X61485 X61486 X61487 XM_006236822 XP_006236884 XM_008763049 XP_008761271 XM_008763050 XP_008761272 NM_012671 NP_036803
|
Function |
TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
|
Subcellular Location |
Transforming growth factor alpha: Secreted, extracellular space.
|
Top Pathways |
Non-small cell lung cancer, Renal cell carcinoma, Pancreatic cancer, Glioma, Prostate cancer
|