Gene Symbol |
Sstr1
|
Entrez Gene |
25033
|
Alt Symbol |
Gpcrrna
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
somatostatin receptor 1
|
Other Description |
RNGPCRRNA|SRIF-2|SS-1-R|SS1-R|SS1R|Somatostatin receptor subtype 1|somatostatin receptor type 1
|
Swissprots |
P28646
|
Accessions |
EDM03458 P28646 L02915 M97656 AAL76096 X62314 CAA44193 XM_006240115 XP_006240177 NM_012719 NP_036851
|
Function |
Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled to phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Brain, pituitary, islet, jejunum, stomach, heart, spleen.
|
Top Pathways |
cAMP signaling pathway, Neuroactive ligand-receptor interaction
|