TCOF1

Gene Symbol TCOF1
Entrez Gene 6949
Alt Symbol MFD1, TCS, TCS1, treacle
Species Human
Gene Type protein-coding
Description Treacher Collins-Franceschetti syndrome 1
Other Description Treacher Collins syndrome protein|nucleolar trafficking phosphoprotein|treacle protein
Swissprots Q99860 Q13428 A0JLU0 Q7Z5W9 Q6SC72 B4E111 Q99408 Q96A52
Accessions AAB40722 AAC51185 EAW61732 EAW61733 EAW61734 EAW61735 EAW61736 EAW61737 EAW61738 EAW61739 Q13428 AB209317 BAD92554 AI419459 AI939467 AK096467 AK225284 AK296918 BAG59473 AK299167 BAG61214 AK303611 BAG64623 AK307586 AL133039 CAB61367 AW135418 AY460334 AAR87774 BC008331 BC011764 AAH11764 BC014559 AAH14559 BC016144 AAH16144 BC027252 AAH27252 BC033093 AAH33093 BM664489 BX537490 DC377932 U40847 AAC50903 U76366 AAC51181 XM_005268502 XP_005268559 XM_005268503 XP_005268560 XM_005268504 XP_005268561 XM_005268505 XP_005268562 XM_005268506 XP_005268563 XM_005268507 XP_005268564 XM_005268508 XP_005268565 XM_005268509 XP_005268566 XM_011537678 XP_011535980 XR_427778 XR_427779 XR_427780 NM_000356 NP_000347 NM_001008657 NP_001008657 NM_001135243 NP_001128715 NM_001135244 NP_001128716 NM_001135245 NP_001128717 NM_001195141 NP_001182070 NM_001008656
Function May be involved in nucleolar-cytoplasmic transport. May play a fundamental role in early embryonic development, particularly in development of the craniofacial complex (By similarity). May participate in certain stages of ribosome biogenesis. {ECO:0000250, ECO:0000269|PubMed:12777385}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:12777385}.
Top Pathways Ribosome biogenesis in eukaryotes

Treacle (H-6) - sc-374536 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Treacle (H-6): sc-374536. Western blot analysis of Treacle expression in Jurkat nuclear extract.

Treacle (L-16) - sc-49529 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Treacle (L-16): sc-49529. Western blot analysis of Treacle expression in Jurkat nuclear extract.

Treacle (H-90) - sc-67196 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Treacle (H-90): sc-67196. Western blot analysis of Treacle expression in Jurkat (A), Ramos (B), A-431 (C) and MCF7 (D) nuclear extracts.

Treacle (L-18) - sc-49530 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Treacle (N-18) - sc-49531 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Treacher Collins syndrome protein antibody - ab187510 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Treacher Collins syndrome protein antibody (ab187510) at 1/500 dilutionLane 1 : BT474 cell extractLane 2 : 293T cell extract

Anti-Treacher Collins syndrome protein antibody - ab57683 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57683 Treacher Collins syndrome protein antibody at 1ug/ml.

Anti-Treacher Collins syndrome protein antibody - ab172201 from Abcam

Host Mouse
Clonality Polyclonal
All lanes : Anti-Treacher Collins syndrome protein antibody (ab172201) at 1 µg/mlLane 1 : Treacher Collins syndrome transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-Treacher Collins syndrome protein antibody - ab37747 from Abcam

Prices $406.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-Treacher Collins syndrome protein antibody - ChIP Grade - ab65212 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Treacher Collins syndrome protein antibody - ChIP Grade (ab65212) at 1/500 dilutionLane 1 : Extracts from Jurkat cellsLane 2 : Extracts from Jurkat cells, plus immunising peptide

Anti-Treacle / TCOF1 Antibody (clone 8H3) - LS-C198318 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8H3
Immunofluorescence of monoclonal antibody to TCOF1 on HeLa cell . [antibody concentration 10 ug/ml]

Anti-Treacle / TCOF1 Antibody (aa41-90) IHC-plus™ - LS-B8409 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Treacle / TCOF1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8409 dilution 5 ug/ml.

Anti-Treacle / TCOF1 Antibody (Gln55) - LS-C191973 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Treacle / TCOF1 Antibody - LS-C341328 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Treacle / TCOF1 Antibody - LS-C335251 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using TCOF1 antibody.

Treacher Collins syndrome protein Antibody (8H3) - H00006949-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8H3
Western Blot: Treacher Collins syndrome protein Antibody (8H3) [H00006949-M02] - Analysis of TCOF1 expression in transfected 293T cell line by TCOF1 monoclonal antibody (M02), clone 8H3.Lane 1: TCOF1 transfected lysate(152.104 KDa).Lane 2: Non-transfected lysate.

Treacher Collins syndrome protein Antibody - NBP1-86909 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Treacher Collins syndrome protein Antibody [NBP1-86909] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: CACO-2

Treacher Collins syndrome protein Antibody - NBP1-86908 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Treacher Collins syndrome protein Antibody [NBP1-86908] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli fibrillar center.

Treacher Collins syndrome protein Antibody - H00006949-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Treacher Collins syndrome protein Antibody [H00006949-B01] - analysis of TCOF1 expression in transfected 293T cell line by TCOF1 MaxPab polyclonal antibody (B01). Lane 1: TCOF1 transfected lysate (96.80 KDa). Lane 2: Non-transfected lysate.

Treacher Collins syndrome protein Antibody - H00006949-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Treacher Collins syndrome protein Antibody - H00006949-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TCOF1, N-Terminal antibody produced in rabbit - SAB4502935 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TCOF1: <B>Cat. No. SAB4502935</B>: Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Anti-TCOF1 antibody. Cells on the left were treated with the Anti-TCOF1 antibody. Cells on the right (negative control) were treated with both Anti-TCOF1 antibody and the synthesized immunogen peptide.

Anti-TCOF1 antibody produced in rabbit - HPA038237 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TCOF1: <B>Cat. No. HPA038237</B>: Immunohistochemical staining of human rectum shows moderate nucleolar and cytoplasmic positivity in glandular cells.

Anti-TCOF1 antibody produced in mouse - SAB1409732 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-TCOF1 antibody produced in chicken - GW22821 from Sigma-Aldrich

Prices $267.50
Sizes 50 µg
Host Chicken
Clonality Polyclonal
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