MMP9

Gene Symbol	MMP9
Entrez Gene	4318
Alt Symbol	CLG4B, GELB, MANDP2, MMP-9
Species	Human
Gene Type	protein-coding
Description	matrix metallopeptidase 9
Other Description	macrophage gelatinase|matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)|matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)|matrix metalloproteinase-9|type V collagenase
Swissprots	Q9UCL1 Q3LR70 P14780 Q8N725 Q9H4Z1 B2R7V9 Q9UDK2 Q9UCJ9
Accessions	AAD37404 AAM97934 ABA03169 BAA20967 CAC07541 EAW75776 P14780 AK298246 BAH12743 AK301446 BAH13483 AK302530 BAH13736 AK303080 BAH13895 AK311648 AK313137 BAG35956 AK316145 BAH14516 AW468235 BC006093 AAH06093 CN288579 DQ896791 ABM87790 EU176415 ABW03866 HQ874462 AEA49029 J05070 AAA51539 NM_004994 NP_004985
Function	May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. {ECO:0000269|PubMed:1480034}.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000305}.
Tissue Specificity	Produced by normal alveolar macrophages and granulocytes.
Top Pathways	Leukocyte transendothelial migration, Bladder cancer, TNF signaling pathway, MicroRNAs in cancer, Estrogen signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MMP9-Over-expression-Lysate - LY10824a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

MMP9 overexpression lysate - LY401553 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MMP9 293 Cell Lysate - 401408 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MMP-9 Overexpression Lysate (Native) - NBL1-13162 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MMP-9 (h2): 293T Lysate - sc-176046 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

MMP9 Over-expression Lysate Product - GWB-C24268 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Human MMP-9 / CLG4B HEK293 Cell Lysate (WB positive control) - 10327-HNAHL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human MMP-9 / CLG4B HEK293 Cell Lysate (WB positive control) - 10327-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human MMP-9 Human Cells Transfected Lysate (positive control) (denatured) - orb172975 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Panoply™ Human MMP9 Knockdown Stable Cell Line - CSC-DC009611 from Creative biogene Category Cell Line Species Human

MMP9 Knockout Cell Line-HeLa - CSC-RT1934 from Creative biogene Category Cell Line Species Human

MMP9 KO Cell Lysate-HeLa - CLKO-1790 from Creative biogene Category Cell Lysate

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