CH25H

Gene Symbol CH25H
Entrez Gene 9023
Alt Symbol C25H
Species Human
Gene Type protein-coding
Description cholesterol 25-hydroxylase
Other Description cholesterol 25-monooxygenase|h25OH
Swissprots B2RBY3 O95992
Accessions AAC97481 CAR81282 CBX84760 EAW50146 O95992 AF059214 AAC97483 AK314865 BAG37380 BC017843 AAH17843 BC072430 AAH72430 DQ892026 ABM82952 DQ895218 ABM86144 NM_003956 NP_003947
Function Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25- hydroxycholesterol by macrophages may play a role in Leydig cell differentiation. {ECO:0000269|PubMed:9852097}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways Primary bile acid biosynthesis

CH25H (H-41) - sc-135228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CH25H (H-41): sc-135228. Western blot analysis of CH25H expression in c4 whole cell lysate.

CH25H (P-15) - sc-107480 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CH25H (P-15): sc-107480. Western blot analysis of CH25H expression in mouse liver tissue extract.

CH25H (C-16) - sc-107479 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CH25H antibody - ab76478 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-CH25H antibody (ab76478) at 5 µg/ml + recombinant fragment of CH25H (plus 26 kDa tag) at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

Anti-CH25H antibody - ab133933 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CH25H antibody (ab133933) at 1 µg/ml + Human fetal brain lysate

Anti-C25H / CH25H Antibody (aa142-247) - LS-C306926 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-C25H / CH25H Antibody (aa190-239) IHC-plus™ - LS-B9764 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-C25H / CH25H antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9764 concentration 10 ug/ml.

CH25H Antibody - H00009023-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

CH25H Antibody (1G8) - H00009023-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G8

CH25H Polyclonal Antibody - bs-6480R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Paraformaldehyde-fixed, paraffin embedded mouse kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with Rabbit Anti-CH25H Polyclonal Antibody, Unconjugated (bs-6480R) at 1:200 overnight at 4°C, followed by a conjugated secondary for 90 minutes and DAB staining.

Monoclonal Anti-CH25H antibody produced in mouse - SAB1403010 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G8
<B>Immunoblotting</B><BR/>Monoclonal Anti-CH25H: <B>Cat. No. SAB1403010</B>: Antibody concentration: 1 μg/mL. Specific band of ~37.7 kDa using immunogen protein lysate.

CH25H Antibody - C-terminal region (ARP65536_P050) - ARP65536_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CH25H Antibody (OABF01697) - OABF01697 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti -CH25H (Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH) - 124919 from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 1G8

Anti -CH25H (Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH) (AP) - 124919-AP from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 1G8

Anti -CH25H (Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH) (Biotin) - 124919-Biotin from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 1G8

Anti -CH25H (Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH) (FITC) - 124919-FITC from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 1G8

Anti -CH25H (Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH) (HRP) - 124919-HRP from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 1G8

Anti -CH25H (Cholesterol 25-hydroxylase, Cholesterol 25-monooxygenase, h25OH) (PE) - 124919-PE from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 1G8

CH25H antibody - H00009023-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

CH25H antibody - H00009023-M01 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G8

CH25H antibody - 16734-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

CH25H, Polyclonal Antibody - MBS2528738 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

CH25H Antibody - EPP11490 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal

Anti-CH25H (aa 206-272) polyclonal antibody - DPAB-DC3706 from Creative Diagnostics

Host Mouse
Clonality Polyclonal
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