| Gene Symbol |
PSMB10
|
| Entrez Gene |
5699
|
| Alt Symbol |
LMP10, MECL1, beta2i
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) subunit, beta type, 10
|
| Other Description |
low molecular mass protein 10|macropain subunit MECl-1|multicatalytic endopeptidase complex subunit MECl-1|proteasome MECl-1|proteasome catalytic subunit 2i|proteasome subunit MECL1|proteasome subunit beta 7i|proteasome subunit beta type-10|proteasome subunit beta-2i
|
| Swissprots |
Q5U098 P40306 B2R5J4
|
| Accessions |
CAA50709 CBX46811 EAW83187 P40306 AK225658 AK298012 BAG60316 AK312208 BAG35141 BC017198 AAH17198 BC052369 AAH52369 BM845639 BM981173 BP289065 BT019723 AAV38528 BT019724 AAV38529 CR456982 CAG33263 Y13640 CAA73982 NM_002801 NP_002792
|
| Function |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.
|
| Subcellular Location |
Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00809}. Nucleus {ECO:0000250}.
|
| Top Pathways |
Proteasome
|