Gene Symbol |
Grid2
|
Entrez Gene |
79220
|
Alt Symbol |
GluD2
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
glutamate receptor, ionotropic, delta 2
|
Other Description |
gluR delta-2 subunit|glutamate receptor delta-2 subunit|glutamate receptor ionotropic, delta-2
|
Swissprots |
Q62641 Q63226
|
Accessions |
EDL91606 EDL91607 Q63226 U08256 AAA17829 Z17239 CAA78937 NM_024379 NP_077355
|
Function |
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Tissue Specificity |
Expressed at high levels in the cerebellar Purkinje cell layer, almost absent in the forebrain. {ECO:0000269|PubMed:8422924}.
|
Top Pathways |
Long-term depression, Neuroactive ligand-receptor interaction
|