PRKAG1

Gene Symbol	PRKAG1
Entrez Gene	5571
Alt Symbol	AMPKG
Species	Human
Gene Type	protein-coding
Description	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Other Description	5'-AMP-activated protein kinase subunit gamma-1|5'-AMP-activated protein kinase, gamma-1 subunit|AMPK gamma-1 chain|AMPK gamma1
Swissprots	P54619 Q8N7V9 B4DDT7
Accessions	EAW58032 EAW58033 P54619 AK097606 BAC05117 AK293332 BAG56848 AK303276 BAG64356 AK307994 AK310250 BC000358 AAH00358 BG772337 BG772412 BI757340 BM667691 BM972308 BT007345 AAP36009 CB124830 DB020277 XM_005269019 XP_005269076 XM_005269020 XP_005269077 XM_006719499 XP_006719562 XM_006719500 XP_006719563 XM_011538562 XP_011536864 NM_001206709 NP_001193638 NM_001206710 NP_001193639 NM_002733 NP_002724 NM_212461
Function	AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating alread
Top Pathways	Non-alcoholic fatty liver disease (NAFLD), Glucagon signaling pathway, AMPK signaling pathway, Oxytocin signaling pathway, Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AMPKγ1 Antibody - 4187 from Cell Signaling Technology Prices $99.00, $246.00 Sizes 20 µl (2 western blots), 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

AMPKγ1/2/3 (H-9) - sc-390579 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

AMPKγ1/2/3 (FL-331) - sc-25793 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

AMPKγ1 (T-20) - sc-19138 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-AMPK gamma 1 antibody - ab85040 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-AMPK gamma 1 antibody [7H3E9] - ab181460 from Abcam Prices $384.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 7H3E9

Anti-AMPK gamma 1 antibody [Y307] - ab32382 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone Y307

Anti-AMPK gamma 1 antibody [Y308] - ab32508 from Abcam Prices $400.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone Y308

Anti-PRKAG1 / AMPK Gamma 1 Antibody - LS-C122653 from LifeSpan Bioscience Prices $465.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody - LS-C146861 from LifeSpan Bioscience Prices $545.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (C-Terminus) - LS-C203279 from LifeSpan Bioscience Prices $245.00 Sizes 40 µg Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (Internal, APC) - LS-C206402 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (Internal, AP) - LS-C206401 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (Internal, Biotin) - LS-C206403 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (Internal, FITC) - LS-C206404 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (Internal, PE) - LS-C206406 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (aa5-33, AP) - LS-C207517 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody - LS-C136840 from LifeSpan Bioscience Prices $255.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (aa5-33, APC) - LS-C207518 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (aa5-33, FITC) - LS-C207520 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (aa5-33, Azide-free, HRP) - LS-C207521 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (aa5-33, Biotin) - LS-C207519 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (aa5-33, PE) - LS-C207522 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (Internal, Azide-free, HRP) - LS-C207937 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PRKAG1 / AMPK Gamma 1 Antibody (aa26-75) - LS-C200525 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

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