Cth

Gene Symbol Cth
Entrez Gene 24962
Alt Symbol H
Species Rat
Gene Type protein-coding
Description cystathionine gamma-lyase
Other Description CTL target antigen|PRB-RA|cystathionase (cystathionine gamma-lyase)|cysteine-protein sulfhydrase|gamma-cystathionase|probasin-related antigen
Swissprots P18757
Accessions CBF67270 CBU92143 EDL82568 P18757 AB052882 BAB19922 AY032875 AAK52091 AY641456 BC078869 AAH78869 D17370 BAA04189 X53460 CAA37547 XM_006233536 XP_006233598 NM_017074 NP_058770
Function Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm.
Top Pathways Glycine, serine and threonine metabolism, Cysteine and methionine metabolism, Selenocompound metabolism, Biosynthesis of amino acids

Cystathionine Gamma Lyase (CSE), Rat, ELISA Kit - SEB538Ra from ARP American Research Products

Category ELISA Kit
Prices $742.00
Sizes 96 t
Sensitivity 0.053ng/mL
Range 0.156-10ng/mL

Cystathionine gamma-lyase, Cth, Rat, ELISA Kit - E1538r from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t

H (+)/Cl (-) exchange transporter 5 (CLCN5), Rat, ELISA Kit - E02H1354 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

ELISA Kit for Cystathionine Gamma Lyase (CSE) - SEB538Ra from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.053ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Rat Cth ELISA Kit - E078568 from Biobool

Category ELISA Kit

CTH ELISA Kit (Rat) (OKEH04230) - OKEH04230 from Aviva Systems Biology

Category ELISA Kit
Prices $596.00
Sizes 96 wells
Sensitivity < 0.39 ng/mL
Range 0.78 - 50 ng/mL

Cystathionine Gamma Lyase (CSE), ELISA Kit - MBS451057 from MyBioSource

Category ELISA Kit
Prices $425.00, $565.00, $2,485.00, $4,830.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity <0.053ng/mL
Range 0.156-10ng/mL
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