Gene Symbol | Pou3f2 |
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Entrez Gene | 18992 |
Alt Symbol | 9430075J19Rik, A230098E07Rik, Brn-2, Brn2, OTF-7, Otf7, oct-7 |
Species | Mouse |
Gene Type | protein-coding |
Description | POU domain, class 3, transcription factor 2 |
Other Description | brain-2 class III POU-domain protein|brain-specific homeobox/POU domain protein 2|nervous system-specific octamer-binding transcription factor N-Oct-3|octamer-binding protein 7|octamer-binding transcription factor 7 |
Swissprots | A2AJY1 P31360 |
Accessions | AAA39961 EDL05540 P31360 AK020487 AK034682 AK039117 AK138672 BAE23742 AK139058 AK164237 BAE37697 BC172622 AAI72622 BC172726 AAI72726 X66602 NM_008899 NP_032925 |
Function | Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed specifically in the neuroectodermal cell lineage. |
Brn-2 CRISPR/Cas9 KO Plasmid (m) - sc-422351 from Santa Cruz Biotechnology
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Brn-2 HDR Plasmid (m) - sc-422351-HDR from Santa Cruz Biotechnology
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Brn-2 Double Nickase Plasmid (m) - sc-422351-NIC from Santa Cruz Biotechnology
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Brn-2 Double Nickase Plasmid (m2) - sc-422351-NIC-2 from Santa Cruz Biotechnology
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Brn-2 CRISPR Activation Plasmid (m) - sc-422351-ACT from Santa Cruz Biotechnology
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Brn-2 CRISPR Activation Plasmid (m2) - sc-422351-ACT-2 from Santa Cruz Biotechnology
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Brn-2 Lentiviral Activation Particles (m) - sc-422351-LAC from Santa Cruz Biotechnology
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Brn-2 Lentiviral Activation Particles (m2) - sc-422351-LAC-2 from Santa Cruz Biotechnology
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Brn-2 siRNA (m) - sc-29838 from Santa Cruz Biotechnology
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Brn-2 shRNA Plasmid (m) - sc-29838-SH from Santa Cruz Biotechnology
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Brn-2 shRNA (m) Lentiviral Particles - sc-29838-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU151431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN39086 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND39086 from Sigma-Aldrich
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POU3F2 siRNA (Mouse) - CRM3168 from Cohesion Biosciences
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shRNA set against Mouse POU3F2 (NM_008899.2) - SHH380080 from Creative biogene
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POU3F2 shRNA Plasmid (Mouse) - CHM3168 from Cohesion Biosciences
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