| Gene Symbol |
STAR
|
| Entrez Gene |
6770
|
| Alt Symbol |
STARD1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
steroidogenic acute regulatory protein
|
| Other Description |
START domain containing 1|START domain-containing protein 1|StAR-related lipid transfer (START) domain containing 1|cholesterol trafficker|mitochondrial steroid acute regulatory protein|steroid acute regulatory protein|steroidogenic acute regulator|steroidogenic acute regulatory protein, mitochondrial
|
| Swissprots |
P49675 Q16396
|
| Accessions |
AAC50234 ABA25863 ABA25864 ABB51615 AER36553 EAW63334 EAW63335 P49675 AF035277 AAB88174 AK090513 AK315122 BAG37577 AL526126 AV706111 AV706872 AV707696 AV708514 AY532319 AAS57684 BC010550 AAH10550 BX647744 CR456803 CAG33084 CR541850 CAG46648 DQ891806 ABM82732 DQ894990 ABM85916 S79669 AAB35726 U17280 AAC50141 XM_006716392 XP_006716455 NM_000349 NP_000340 NM_001007243
|
| Function |
Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
|
| Subcellular Location |
Mitochondrion.
|
| Tissue Specificity |
Expressed in gonads, adrenal cortex and kidney.
|
| Top Pathways |
Ovarian steroidogenesis
|
