CRYAA

Gene Symbol CRYAA
Entrez Gene 281718
Alt Symbol -
Species Bovine
Gene Type protein-coding
Description crystallin, alpha A
Other Description alpha-crystallin A chain
Swissprots P02470
Accessions DAA32986 P02470 M26142 AAA30471 NM_174289 NP_776714
Function Contributes to the transparency and refractive index of the lens (By similarity). Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. {ECO:0000250, ECO:0000269|PubMed:20440841}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. {ECO:0000250}.
Top Pathways Protein processing in endoplasmic reticulum

Anti-alpha A Crystallin antibody - ab5595 from Abcam

Prices $382.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab5595 staining alpha A Crystallin in non-transgenic 13.5 mouse embryos by Immunohistochemistry (PFA fixed, paraffin embedded sections).Heads of mice were removed, fixed in 10% formalin, dehydrated, embedded in paraffin, sectioned (5-7 µm).Slides containing ocular sections from non-transgenic embryos were first deparaffinized and rehydrated. Antigens were retrieved by microwave treatment in 10 mM Sodium Citrate buffer (pH 6.0). Following antigen retrieval, the tissue sections were blocked with 10% normal horse serum for 30 minutes, at room temperature. The slides were then incubated with ab5595 at a 1/10,000 dilution overnight at 4°C. Following brief washes in PBS, the slides were incubated with the appropriate biotinylated-secondary antibodies for 30 minutes at 37°C. Antigen-antibody complexes were then detected using streptavidin-linked Alexa 594 (red) at 1/1000 dilution. Sections were mounted using anti-fade media containing DAPI (blue). Images were captured using a Nikon Eclipse E6

Anti-alpha A Crystallin antibody - ab69552 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-alpha A Crystallin antibody (ab69552) at 1/1000 dilution + bovine alpha A Crystallin protein

Anti-alpha A Crystallin antibody [1H3.B8] - ab78439 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H3.B8
Anti-alpha A Crystallin antibody [1H3.B8] (ab78439) at 1/1000 dilution + Mouse eye lens whole cell lysate at 25 µgSecondaryHRP-conjugated Goat anti-Mouse polyclonal at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-alpha A Crystallin antibody [2C3] - ab139337 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C3
All lanes : Anti-alpha A Crystallin antibody [2C3] (ab139337) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY alpha A Crystallin cDNA.Lysates/proteins at 5 µg per lane.

Anti -Crystallin, alpha A - C7944-50 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -Crystallin, alpha A - C7944-51 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

CRYAA Polyclonal Antibody - PA1-009 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot detection of alpha-A crystallin from bovine lens extract using PA1-009.

Crystallin, alpha A - ARB-62367 from Nordic BioSite

Host Sheep
Clone polyclonal
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