ST8SIA1

Gene Symbol ST8SIA1
Entrez Gene 6489
Alt Symbol GD3S, SIAT8, SIAT8-A, SIAT8A, ST8SiaI
Species Human
Gene Type protein-coding
Description ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Other Description alpha-2,8-sialyltransferase 8A|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase|disialoganglioside (GD3) synthase|ganglioside GD3 synthase|ganglioside GT3 synthase|ganglioside-specific alpha-2,8-polysialyltransferase|sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A|sialyltransferase 8A (alpha-N-acetylneuraminate: alpha-2,8-sialyltransferase, GD3 synthase)|sialyltransferase St8Sia I|sialytransferase St8Sia I
Swissprots Q93064 Q92185 Q17RL0 A8K4H6 Q6PZN5
Accessions CAS91695 EAW96468 EAW96469 EAW96470 EAW96471 Q92185 AF088002 AK290941 BAF83630 AK297310 BAG59776 AK315340 BAG37739 AY569975 AAS75783 BC031081 BC046158 AAH46158 BC117285 AAI17286 BC126162 AAI26163 BM929838 D26360 BAA05391 EU041716 ABU62753 HQ258201 ADR82955 L32867 AAA62366 L43494 AAC37586 X77922 CAA54891 XM_005253470 XP_005253527 XM_011520817 XP_011519119 XR_931322 NM_001304450 NP_001291379 NM_003034 NP_003025
Function Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. {ECO:0000269|PubMed:7937974, ECO:0000269|PubMed:8058740, ECO:0000269|PubMed:8195250, ECO:0000269|PubMed:8631981}.
Subcellular Location Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity Strongly expressed in melanoma cell lines, adult and fetal brain and to a lesser extent in adult and fetal lung. {ECO:0000269|PubMed:7937974, ECO:0000269|PubMed:8631981}.
Top Pathways Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series, Glycosphingolipid biosynthesis - ganglio series

GD3 Synthase (H-76) - sc-99093 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GD3 Synthase (H-76): sc-99093. Western blot analysis of GD3 Synthase expression in non-transfected: sc-117752 (A) and mouse GD3 Synthase transfected: sc-120460 (B) 293T whole cell lysates.

GD3 Synthase (K-18) - sc-46984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GD3 Synthase (K-18): sc-46984. Western blot analysis of GD3 Synthase expression in human liver tissue extract.

GD3 Synthase (C-14) - sc-46982 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GD3 Synthase (C-14): sc-46982. Western blot analysis of GD3 Synthase expression in human liver tissue extract.

Anti-ST8SIA1 antibody - ab37806 from Abcam

Prices $406.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-ST8SIA1 antibody (ab37806) at 1/2000 dilution + E. coli derived fusion protein at 2.5 µgSecondaryHRP conjugated Goat anti IgY at 1/1000 dilution

Anti-ST8SIA1 Antibody (N-Terminus) - LS-C201490 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human OVCAR-3. ST8SIA1 antibody dilution 1.0 ug/ml.

ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Antibody [Unconjugated] - AF6716 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of Hs 294T human melanoma cell line, SK‑Mel‑28 human malignant melanoma cell line, A375 human melanoma cell line, and Bowes human melanoma cell line. PVDF membrane was probed with 2 µg/mL of Sheep Anti-Human ST8 alpha ‑2,8‑Sialyltransferase 8A/ST8SIA1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6716) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for ST8 alpha ‑2,8‑Sialyltransferase 8A/ST8SIA1 at approximately 48‑50 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Antibody (MB3.6) - NBP2-29826 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MB3.6
Immunocytochemistry/Immunofluorescence: ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Antibody (MB3.6) [NBP2-29826] - Ganglioside GD3 (NBP2-29826; red) and GP2 (green) on human pancreas, 200x. Image from verified customer review.

ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Antibody - NBP1-80750 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Antibody [NBP1-80750] - Analysis in control (vector only transfected HEK293T lysate) and sT8SIA1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Antibody - NB100-75632 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-ST8SIA1 )

ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Antibody (4F6) - NB120-6217 from Novus Biologicals

Prices $299.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone 4F6

Anti-ST8SIA1 antibody produced in chicken - GW22921 from Sigma-Aldrich

Prices $267.50
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-ST8SIA1 antibody produced in rabbit - HPA026775 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ST8SIA1: <B>Cat. No. HPA026775</B>: Immunohistochemical staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.

ST8SIA1 Antibody - N-terminal region (ARP45413_P050) - ARP45413_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Human ST8 alpha -2,8‑Sialyltransferase 8A/ ST8SIA1 Antibody - AF6716 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Detection of Human ST8 a-2,8-Sialyltransferase 8A/ ST8SIA1 by Western Blot. Western blot shows lysates of Hs 294T human melanoma cell line, SK-Mel-28 human malignant melanoma cell line, A375 human melanoma cell line, and Bowes human melanoma cell line. PVDF membrane was probed with 2 µg/mL of Sheep Anti-Human ST8 a-2,8-Sialyltransferase 8A/ST8SIA1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6716) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016 ). A specific band was detected for ST8 a-2,8-Sialyltransferase 8A/ST8SIA1 at approximately 48-50 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .

Human ST8SIA1 Affinity Purified Polyclonal Ab, Sheep IgG - AF6716-SP from R&D Systems

Host Sheep
Clonality Polyclonal
Detection of Human ST8  alpha ‑2,8‑Sialyltransferase 8A/ST8SIA1 by Western Blot.Western blot shows lysates of Hs 294T human melanoma cell line, SK‑Mel‑28 human malignant melanoma cell line, A375 human melanoma cell line, and Bowes human melanoma cell line. PVDF membrane was probed with 2 µg/mL of Sheep Anti-Human ST8 alpha ‑2,8‑Sialyltransferase 8A/ST8SIA1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6716) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for ST8 alpha ‑2,8‑Sialyltransferase 8A/ST8SIA1 at approximately 48‑50 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

ST8SIA1 antibody - 24918-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 24918-1-AP( ST8SIA1 Antibody) at dilution of 1:1000

ST8SIA1 antibody - H00006489-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

ST8SIA1 Antibody - XW-8145 from ProSci

Prices $325.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

ST8SIA1 antibody - 24918-1-AP from Proteintech Group

Prices $279.00
Sizes con: 40 μg/150μl
Host Rabbit
Clonality Polyclonal
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 24918-1-AP( ST8SIA1 Antibody) at dilution of 1:1000

Ganglioside GD3 Antibody - GWB-C5EA41 from Genway Biotech

Prices $483.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone R24

ST8SIA1 Monoclonal Antibody (R24) - MA1-25302 from Thermo Fisher Scientific

Prices $399.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone R24

ST8SIA1 Antibody - PA1-27922 from Thermo Fisher Scientific

Prices $425.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

St8sia1-Antibody-middle-region-AI12575 - AI12575 from Abgent, a WuXi AppTec company

Prices $293.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Host: Rabbit Target Name: St8sia1 Sample Tissue: Rat Heart lysates Antibody Dilution: 1.0ug/ml

ST8SIA1-Antibody-N-terminal-region-AI12574 - AI12574 from Abgent, a WuXi AppTec company

Prices $293.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Host: Rabbit Target Name: ST8SIA1 Sample Tissue: OVCAR-3 Whole cell lysates Antibody Dilution: 1.0ug/ml

ST8SIA1 - A9648 from NeoScientific

Prices $480.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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