CDKN2C

Gene Symbol CDKN2C
Entrez Gene 1031
Alt Symbol INK4C, p18, p18-INK4C
Species Human
Gene Type protein-coding
Description cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Other Description CDK6 inhibitor p18|cyclin-dependent inhibitor|cyclin-dependent kinase 4 inhibitor C|cyclin-dependent kinase 6 inhibitor p18|p18-INK6
Swissprots Q8TB83 P42773
Accessions AAC39783 AAF28398 AAM11873 CBX47327 EAX06833 EAX06834 EAX06835 EAX06836 P42773 AF041248 AAC39782 AK021794 AK091170 BAG52297 BC000598 AAH00598 BC005041 AAH05041 BC016173 AAH16173 BC017036 BE783451 BE831176 CR450289 CAG29285 DQ891516 ABM82442 DQ894707 ABM85633 U17074 AAC50074 NM_001262 NP_001253 NM_078626 NP_523240
Function Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
Tissue Specificity Highest levels found in skeletal muscle. Also found in pancreas and heart.
Top Pathways Cell cycle, HTLV-I infection, Transcriptional misregulation in cancer

p18 INK4C (DCS118) Mouse mAb - 2896 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 200 µl (20 western blots)
Host Mouse
Clonality Monoclonal
Clone DCS118
Western blot analysis of extracts from HeLa, 293 and Ramos cells, using p18 INK4C (DCS118) Mouse mAb.

p18 (DCS-118) - sc-56332 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
p18 (DCS-118): sc-56332. Western blot analysis of p18 expression in non-transfected: sc-117752 (A) and human p18 transfected: sc-174498 (B) 293T whole cell lysates.

p18 (M-168) - sc-1208 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
p18 (M-168): sc-1208. Western blot analysis of p18 expression in NIH/3T3 nuclear extract.

p18 (C-19) - sc-864 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p18 (C-19): sc-864. Western blot analysis of mouse recombinant p18 fusion protein.

p18 (N-20) - sc-865 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of p18 expression in NIH/3T3 nuclear extracts (A,B). Antibodies tested include p18 (N-20): sc-865 (A) and p18 (M-20): sc-1064 (B).

p18 (118.2) - sc-9965 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
p18 (118.2): sc-9965. Western blot analysis of p18 expression in COLO 320DM whole cell lysate.

p18 (18P118) - sc-65477 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
p18 (18P118): sc-65477. Western blot analysis of p18 expression in non-transfected: sc-117752 (A) and human p18 transfected: sc-174498 (B) 293T whole cell lysates.

p18 (M-20) - sc-1064 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
p18 (M-20)-G: sc-1064-G. Western blot analysis of mouse recombinant p18 fusion protein.

Anti-p18 INK4c antibody - ab66748 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Standard Curve for p18 INK4c (Analyte: p18 INK4c protein (T7 Tag) (ab40127)); dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [18P118 (same as DCS-118)] to p18 INK4c (ab3216) at 5ug/ml and Detector Antibody Rabbit polyclonal to p18 INK4c (ab66748) at 0.5ug/ml.

Anti-p18 INK4c antibody - ab37738 from Abcam

Prices $406.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-p18 INK4c antibody - ab53035 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-p18 INK4c antibody (ab53035) at 1/500 dilutionLane 1 : Cos7 cell extractLane 2 : Cos7 cell extract with peptide

Anti-p18 INK4c antibody [18P118] - ab80625 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 18P118
Formalin-fixed, paraffin-embedded human tonsil stained with 1/50 ab80625 using a peroxidase-conjugated secondary antibody and an AEC chromogen. Note nuclear staining of cells.

Anti-p18 INK4c antibody [18P118 (same as DCS-118)] - ab3216 from Abcam

Host Mouse
Clonality Monoclonal
Clone 18P118 (same as DCS-118)
Standard Curve for p18 INK4c (Analyte: p18 INK4c protein (T7 Tag) (ab40127)); dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [18P118 (same as DCS-118)] to p18 INK4c (ab3216) at 5ug/ml and Detector Antibody Rabbit polyclonal to p18 INK4c (ab66748) at 0.5ug/ml.

Anti-p18 INK4c antibody [2E1] - ab156755 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E1
All lanes : Anti-p18 INK4c antibody [2E1] (ab156755) at 1/2000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY controlLane 2 : HEK293T cells transfected with pCMV6-ENTRY p18 INK4cLysates/proteins at 5 µg per lane.

Anti-p18 INK4c antibody [EPR15891] - ab192239 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15891
Western blot analysis of immunoprecipitation pellet from HeLa lysate immunoprecipitated using ab192239 at 1/30 dilution.Secondary: Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution. 

Anti-p18 INK4c antibody [SPM305], prediluted - ab54325 from Abcam

Prices $370.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone SPM305
ab54325 staining p18 INK4c in formalin fixed, paraffin embedded human tonsil tissue.

Anti-CDKN2C / p18 INK4c Antibody (clone 1E4) - LS-C175547 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN2C (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKN2C.

Anti-CDKN2C / p18 INK4c Antibody (clone 5G1) - LS-C336322 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5G1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN2C (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKN2C.

Anti-CDKN2C / p18 INK4c Antibody - LS-C37970 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-CDKN2C / p18 INK4c Antibody (clone 18P118, Azide-free) - LS-C88521 from LifeSpan Bioscience

Prices $620.00, $925.00
Sizes 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone 18P118

Anti-CDKN2C / p18 INK4c Antibody (clone 18P118) - LS-C88520 from LifeSpan Bioscience

Prices $280.00, $555.00, $850.00
Sizes 20 µg, 500 µl, 200 µg
Host Mouse
Clonality Monoclonal
Clone 18P118
Formalin-fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and AEC chromogen. Note nuclear staining of cells.

Anti-CDKN2C / p18 INK4c Antibody (aa111-160) - LS-C118543 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using p18 INK Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CDKN2C / p18 INK4c Antibody (aa113-139, AP) - LS-C208387 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDKN2C / p18 INK4c Antibody (aa113-139, APC) - LS-C208388 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDKN2C / p18 INK4c Antibody (aa113-139, Biotin) - LS-C208393 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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