Baat

Gene Symbol Baat
Entrez Gene 12012
Alt Symbol AI118337, AI158864, BAT
Species Mouse
Gene Type protein-coding
Description bile acid-Coenzyme A: amino acid N-acyltransferase
Other Description BACAT|bile acid-CoA:amino acid N-acyltransferase|bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase|glycine N-choloyltransferase|long-chain fatty-acyl-CoA hydrolase|taurine N-acyltransferase
Swissprots Q8C1I3 Q91X34 O08833 A2AKK7
Accessions EDL02319 Q91X34 AA255212 AK017923 BAC25534 BB800891 BC012683 BY080271 CB947692 U95215 AAB58325 XM_006537565 XP_006537628 NM_007519 NP_031545
Function Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain sat
Subcellular Location Cytoplasm {ECO:0000250}. Peroxisome {ECO:0000250}. Note=Cytoplasmic or/and peroxisomal. {ECO:0000250}.
Tissue Specificity Highly expressed in liver, kidney, gallbladder, proximal intestine and distal intestine. Weakly expressed in adrenal gland, lung, brain and muscle. {ECO:0000269|PubMed:12810727, ECO:0000269|PubMed:9215542}.
Top Pathways Primary bile acid biosynthesis, Peroxisome, Bile secretion, Taurine and hypotaurine metabolism, Biosynthesis of unsaturated fatty acids

Bile acid-CoA:amino acid N-acyltransferase (BAAT), Mouse, ELISA Kit - E03B0733 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Mouse Baat ELISA Kit - E045852 from Biobool

Category ELISA Kit
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