| Gene Symbol |
CRYM
|
| Entrez Gene |
1428
|
| Alt Symbol |
DFNA40, THBP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
crystallin, mu
|
| Other Description |
NADP-regulated thyroid-hormone binding protein|ketimine reductase mu-crystallin|mu-crystallin homolog|thiomorpholine-carboxylate dehydrogenase
|
| Swissprots |
D5MNX0 Q5HYB7 Q14894
|
| Accessions |
AAB67600 AAB94938 EAW66862 EAW66863 Q14894 AK290852 BAF83541 AK310424 BC008398 BC018061 AAH18061 BG033512 BI860684 BX648477 CAI46030 DQ892377 ABM83303 DQ895591 ABM86517 L02950 AAC16914 U85772 AAB81564 XM_011545740 XP_011544042 NM_001888 NP_001879 NM_001014444
|
| Function |
Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors. {ECO:0000269|PubMed:21332720}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Expressed in neural tissue, muscle and kidney.
|