| Gene Symbol |
NEU2
|
| Entrez Gene |
4759
|
| Alt Symbol |
SIAL2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sialidase 2 (cytosolic sialidase)
|
| Other Description |
N-acetyl-alpha-neuraminidase 2|cytosolic sialidase|neuraminidase 2|sialidase-2
|
| Swissprots |
Q3KNW4 Q9Y3R4 Q6NTB4
|
| Accessions |
AAY24360 CAB41449 EAW71028 Q9Y3R4 BC069151 AAH69151 BC107053 AAI07054 XM_011511241 XP_011509543 NM_005383 NP_005374
|
| Function |
Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins, oligosaccharides and gangliosides. {ECO:0000269|PubMed:14613940, ECO:0000269|PubMed:22228546}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2-D1. {ECO:0000269|PubMed:10191093}.
|
| Top Pathways |
Sphingolipid metabolism, Other glycan degradation
|
